Association of TGF-beta1, CD14, IL-4, IL-4R and ADAM33 gene polymorphisms with asthma severity in children and adolescents

To verify the association of transforming growth factor-beta1(TGF-beta1) (C-509T and T869C), CD14 (C-159T), IL-4 (C-590T), IL-4R (ILe50Val) and ADAM33 (S_2) gene polymorphisms with asthma severity in a sample of patients with mild, moderate and severe persistent atopic asthma. A clinical, laboratory...

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Veröffentlicht in:	Jornal de pediatria 2008-05, Vol.84 (3), p.203-210
Hauptverfasser:	de Faria, Isabel C J, de Faria, Elisangela J, Toro, Adyléia A D C, Ribeiro, José Dirceu, Bertuzzo, Carmen Silvia
Format:	Artikel
Sprache:	eng
Schlagworte:	ADAM Proteins - genetics Adolescent Asthma - genetics Case-Control Studies Child Cytokines - genetics Female Genetic Markers - genetics Genotype Humans Interleukin-4 - genetics Lipopolysaccharide Receptors - genetics Male Phenotype Polymerase Chain Reaction Polymorphism, Genetic - genetics Prospective Studies Receptors, Immunologic - genetics Receptors, Interleukin-4 - genetics Severity of Illness Index Transforming Growth Factor beta1 - genetics
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