Development of polyvinyl alcohol–sodium alginate gel-matrix-based wound dressing system containing nitrofurazone

Polyvinyl alcohol (PVA)/sodium alginate (SA) hydrogel matrix-based wound dressing systems containing nitrofurazone (NFZ), a topical anti-infective drug, were developed using freeze–thawing method. Aqueous solutions of nitrofurazone and PVA/SA mixtures in different weight ratios were mixed homogeneou...

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Veröffentlicht in:	International journal of pharmaceutics 2008-07, Vol.359 (1), p.79-86
Hauptverfasser:	Kim, Jong Oh, Park, Jung Kil, Kim, Jeong Hoon, Jin, Sung Giu, Yong, Chul Soon, Li, Dong Xun, Choi, Jun Young, Woo, Jong Soo, Yoo, Bong Kyu, Lyoo, Won Seok, Kim, Jung-Ae, Choi, Han-Gon
Format:	Artikel
Sprache:	eng
Schlagworte:	Adsorption Alginates - chemistry Animals Anti-Infective Agents - administration & dosage Bandages Biological and medical sciences Blood Proteins - metabolism Disease Models, Animal Drug Stability General pharmacology Glucuronic Acid - chemistry Hexuronic Acids - chemistry Hydrogel Hydrogels Male Medical sciences Nitrofurazone Nitrofurazone - administration & dosage Pharmaceutical technology. Pharmaceutical industry Pharmacology. Drug treatments Polyvinyl alcohol Polyvinyl Alcohol - chemistry Rats Rats, Sprague-Dawley Sodium alginate Temperature Tensile Strength Wound dressing Wound Healing - drug effects Wounds and Injuries - drug therapy
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