Improvement in Burn Wound Infection and Survival with Antimicrobial Peptide D2A21 (Demegel)

Naturally occurring antimicrobial peptides have been discovered in both plants and animals. Many of these peptides demonstrate impaired activity or cytotoxicity when applied exogenously. Synthetically engineered antimicrobial peptides have been designed to increase potency and activity against bacte...

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Veröffentlicht in:	Plastic and reconstructive surgery (1963) 2002-04, Vol.109 (4), p.1338-1343
Hauptverfasser:	Chalekson, Charles P, Neumeister, Michael W, Jaynes, Jesse
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anti-Bacterial Agents - administration & dosage Anti-Bacterial Agents - pharmacology Anti-Bacterial Agents - therapeutic use Anti-Infective Agents - administration & dosage Anti-Infective Agents - pharmacology Anti-Infective Agents - therapeutic use Biological and medical sciences Burns Burns - complications Burns - mortality Disease Models, Animal Male Medical sciences Peptides Pharmacology. Drug treatments Pseudomonas aeruginosa - drug effects Pseudomonas Infections - drug therapy Pseudomonas Infections - mortality Rats Rats, Wistar Skin, nail, hair, dermoskeleton Traumas. Diseases due to physical agents Wound Infection - drug therapy Wound Infection - mortality
Online-Zugang:	Volltext
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