Complications in Long Fusions to the Sacrum for Adult Scoliosis : Minimum Five-Year Analysis of Fifty Patients

A retrospective study of complications with minimal 5-year follow-up of 50 adults with scoliosis with fusion from T10 or higher to S1. To document the perioperative and long-term complications and instrumentation problems, and to attempt to determine variables which may influence these problems. It...

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Veröffentlicht in:Spine (Philadelphia, Pa. 1976) Pa. 1976), 2008-06, Vol.33 (13), p.1478-1483
Hauptverfasser: WEISTROFFER, Joseph K, PERRA, Joseph H, LONSTEIN, John E, SCHWENDER, James D, GARVEY, Timothy A, TRANSFELDT, Ensor E, OGILVIE, James W, DENIS, Francis, WINTER, Robert B, WROBLEWSKI, Jill M
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container_end_page 1483
container_issue 13
container_start_page 1478
container_title Spine (Philadelphia, Pa. 1976)
container_volume 33
creator WEISTROFFER, Joseph K
PERRA, Joseph H
LONSTEIN, John E
SCHWENDER, James D
GARVEY, Timothy A
TRANSFELDT, Ensor E
OGILVIE, James W
DENIS, Francis
WINTER, Robert B
WROBLEWSKI, Jill M
description A retrospective study of complications with minimal 5-year follow-up of 50 adults with scoliosis with fusion from T10 or higher to S1. To document the perioperative and long-term complications and instrumentation problems, and to attempt to determine variables which may influence these problems. It is not a study of curve correction, balance, or functional outcome. Several previous studies from this and other centers have shown a relatively high complication rate for this select group of patients. Various fusion techniques (anterior, posterior, autograft, allograft), various instrumentation techniques, and various immobilization techniques have created confusion as to the best methodology to employ. Minimal 2-year follow-ups have been standard, but longer follow-ups have shown additional problems. The study cohort consisted of 50 adult patients from a single center who had undergone corrective scoliosis surgery from T10 or higher to the sacrum and who had at least a 5-year minimum follow-up. The mean age was 54 years (range, 18-72), and the mean follow-up was 9.7 years (range, 5-26). All radiographs, office charts, and hospital charts were combed by an independent investigator for complications, which were divided into major and minor, as well as early, intermediate and late. The curvature values and corrections were the subject of a different article, and were not included in this study. There were no deaths or spinal cord injuries. Six patients had nerve root complications, 4 of which totally recovered. Pseudarthrosis was seen in 24% of the patients, only 25% of which were detected within the 2-year follow-up period. Pseudarthrosis was most common at the lumbosacral level. There was no statistical difference in the pseudarthrosis rate between patients with sacral-only fixation versus iliac fixation. Painful implants requiring removal were noted in 11 of the 50 patients. Long fusions to the sacrum in adults with scoliosis continue to have a high complication rate. As compared to the original publications in the 1980s (Kostuik and Hall, Spine 1983;8:489-500; Balderston et al, Spine 1986;11:824-9) the more recent articles have shown a reduction, but not elimination of the pseudarthrosis problem using segmental instrumentation and anterior fusion of the lumbar spine coupled with structural interbody grafting at L4-L5 and L5-S1. Two-year follow-up is inadequate as pseudarthrosis and painful implants often are detected later. Only 3 of the 12 patients with pse
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To document the perioperative and long-term complications and instrumentation problems, and to attempt to determine variables which may influence these problems. It is not a study of curve correction, balance, or functional outcome. Several previous studies from this and other centers have shown a relatively high complication rate for this select group of patients. Various fusion techniques (anterior, posterior, autograft, allograft), various instrumentation techniques, and various immobilization techniques have created confusion as to the best methodology to employ. Minimal 2-year follow-ups have been standard, but longer follow-ups have shown additional problems. The study cohort consisted of 50 adult patients from a single center who had undergone corrective scoliosis surgery from T10 or higher to the sacrum and who had at least a 5-year minimum follow-up. The mean age was 54 years (range, 18-72), and the mean follow-up was 9.7 years (range, 5-26). All radiographs, office charts, and hospital charts were combed by an independent investigator for complications, which were divided into major and minor, as well as early, intermediate and late. The curvature values and corrections were the subject of a different article, and were not included in this study. There were no deaths or spinal cord injuries. Six patients had nerve root complications, 4 of which totally recovered. Pseudarthrosis was seen in 24% of the patients, only 25% of which were detected within the 2-year follow-up period. Pseudarthrosis was most common at the lumbosacral level. There was no statistical difference in the pseudarthrosis rate between patients with sacral-only fixation versus iliac fixation. Painful implants requiring removal were noted in 11 of the 50 patients. Long fusions to the sacrum in adults with scoliosis continue to have a high complication rate. As compared to the original publications in the 1980s (Kostuik and Hall, Spine 1983;8:489-500; Balderston et al, Spine 1986;11:824-9) the more recent articles have shown a reduction, but not elimination of the pseudarthrosis problem using segmental instrumentation and anterior fusion of the lumbar spine coupled with structural interbody grafting at L4-L5 and L5-S1. Two-year follow-up is inadequate as pseudarthrosis and painful implants often are detected later. Only 3 of the 12 patients with pseudarthrosis were detected within the first 2 years after surgery.</description><identifier>ISSN: 0362-2436</identifier><identifier>EISSN: 1528-1159</identifier><identifier>DOI: 10.1097/BRS.0b013e3181753c53</identifier><identifier>PMID: 18520944</identifier><identifier>CODEN: SPINDD</identifier><language>eng</language><publisher>Philadelphia, PA: Lippincott</publisher><subject>Adult ; Aged ; Biological and medical sciences ; Cerebrospinal fluid. Meninges. 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Leukoencephalitis ; Nervous system (semeiology, syndromes) ; Neurology ; Pain, Postoperative - etiology ; Pain, Postoperative - surgery ; Pseudarthrosis - diagnostic imaging ; Pseudarthrosis - etiology ; Radiculopathy - etiology ; Radiography ; Reoperation ; Retrospective Studies ; Sacrum - diagnostic imaging ; Sacrum - surgery ; Scoliosis - diagnostic imaging ; Scoliosis - surgery ; Spinal Fusion - adverse effects ; Spinal Fusion - instrumentation ; Thoracic Vertebrae - diagnostic imaging ; Thoracic Vertebrae - surgery ; Time Factors ; Treatment Outcome</subject><ispartof>Spine (Philadelphia, Pa. 1976), 2008-06, Vol.33 (13), p.1478-1483</ispartof><rights>2008 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c313t-30d95b84b8ede910705b42dc68a83d1e685354bb8c760fb06d36086d6806e7543</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,777,781,27905,27906</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&amp;idt=20390485$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/18520944$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>WEISTROFFER, Joseph K</creatorcontrib><creatorcontrib>PERRA, Joseph H</creatorcontrib><creatorcontrib>LONSTEIN, John E</creatorcontrib><creatorcontrib>SCHWENDER, James D</creatorcontrib><creatorcontrib>GARVEY, Timothy A</creatorcontrib><creatorcontrib>TRANSFELDT, Ensor E</creatorcontrib><creatorcontrib>OGILVIE, James W</creatorcontrib><creatorcontrib>DENIS, Francis</creatorcontrib><creatorcontrib>WINTER, Robert B</creatorcontrib><creatorcontrib>WROBLEWSKI, Jill M</creatorcontrib><title>Complications in Long Fusions to the Sacrum for Adult Scoliosis : Minimum Five-Year Analysis of Fifty Patients</title><title>Spine (Philadelphia, Pa. 1976)</title><addtitle>Spine (Phila Pa 1976)</addtitle><description>A retrospective study of complications with minimal 5-year follow-up of 50 adults with scoliosis with fusion from T10 or higher to S1. To document the perioperative and long-term complications and instrumentation problems, and to attempt to determine variables which may influence these problems. It is not a study of curve correction, balance, or functional outcome. Several previous studies from this and other centers have shown a relatively high complication rate for this select group of patients. Various fusion techniques (anterior, posterior, autograft, allograft), various instrumentation techniques, and various immobilization techniques have created confusion as to the best methodology to employ. Minimal 2-year follow-ups have been standard, but longer follow-ups have shown additional problems. The study cohort consisted of 50 adult patients from a single center who had undergone corrective scoliosis surgery from T10 or higher to the sacrum and who had at least a 5-year minimum follow-up. The mean age was 54 years (range, 18-72), and the mean follow-up was 9.7 years (range, 5-26). All radiographs, office charts, and hospital charts were combed by an independent investigator for complications, which were divided into major and minor, as well as early, intermediate and late. The curvature values and corrections were the subject of a different article, and were not included in this study. There were no deaths or spinal cord injuries. Six patients had nerve root complications, 4 of which totally recovered. Pseudarthrosis was seen in 24% of the patients, only 25% of which were detected within the 2-year follow-up period. Pseudarthrosis was most common at the lumbosacral level. There was no statistical difference in the pseudarthrosis rate between patients with sacral-only fixation versus iliac fixation. Painful implants requiring removal were noted in 11 of the 50 patients. Long fusions to the sacrum in adults with scoliosis continue to have a high complication rate. As compared to the original publications in the 1980s (Kostuik and Hall, Spine 1983;8:489-500; Balderston et al, Spine 1986;11:824-9) the more recent articles have shown a reduction, but not elimination of the pseudarthrosis problem using segmental instrumentation and anterior fusion of the lumbar spine coupled with structural interbody grafting at L4-L5 and L5-S1. Two-year follow-up is inadequate as pseudarthrosis and painful implants often are detected later. Only 3 of the 12 patients with pseudarthrosis were detected within the first 2 years after surgery.</description><subject>Adult</subject><subject>Aged</subject><subject>Biological and medical sciences</subject><subject>Cerebrospinal fluid. Meninges. Spinal cord</subject><subject>Device Removal</subject><subject>Follow-Up Studies</subject><subject>Humans</subject><subject>Lumbar Vertebrae - diagnostic imaging</subject><subject>Lumbar Vertebrae - surgery</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Multiple sclerosis and variants. Guillain barré syndrome and other inflammatory polyneuropathies. Leukoencephalitis</subject><subject>Nervous system (semeiology, syndromes)</subject><subject>Neurology</subject><subject>Pain, Postoperative - etiology</subject><subject>Pain, Postoperative - surgery</subject><subject>Pseudarthrosis - diagnostic imaging</subject><subject>Pseudarthrosis - etiology</subject><subject>Radiculopathy - etiology</subject><subject>Radiography</subject><subject>Reoperation</subject><subject>Retrospective Studies</subject><subject>Sacrum - diagnostic imaging</subject><subject>Sacrum - surgery</subject><subject>Scoliosis - diagnostic imaging</subject><subject>Scoliosis - surgery</subject><subject>Spinal Fusion - adverse effects</subject><subject>Spinal Fusion - instrumentation</subject><subject>Thoracic Vertebrae - diagnostic imaging</subject><subject>Thoracic Vertebrae - surgery</subject><subject>Time Factors</subject><subject>Treatment Outcome</subject><issn>0362-2436</issn><issn>1528-1159</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2008</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpdkEtPwzAQhC0EouXxDxDyBW6BdfyIw61UFJCKQBQOnCLHccAosUucIPXf40IFEqfV7nwz0g5CRwTOCOTZ-eXj4gxKINRQIknGqeZ0C40JT2VCCM-30RioSJOUUTFCeyG8A4CgJN9FIyJ5CjljY-Smvl02VqveehewdXju3SueDeF77z3u3wxeKN0NLa59hyfV0PR4oX1jfbABX-A762wb1Zn9NMmLUZFxqlmtRV_Ha92v8EPMN64PB2inVk0wh5u5j55nV0_Tm2R-f307ncwTTQntEwpVzkvJSmkqkxPIgJcsrbSQStKKGCE55awspc4E1CWIigqQohIShMk4o_vo9Cd32fmPwYS-aG3QpmmUM34IRUYEzVKeRZD9gLrzIXSmLpadbVW3KggU656L2HPxv-doO97kD2Vrqj_TptgInGwAFbRq6k45bcMvlwLNgcUvvgAXf4YK</recordid><startdate>20080601</startdate><enddate>20080601</enddate><creator>WEISTROFFER, Joseph K</creator><creator>PERRA, Joseph H</creator><creator>LONSTEIN, John E</creator><creator>SCHWENDER, James D</creator><creator>GARVEY, Timothy A</creator><creator>TRANSFELDT, Ensor E</creator><creator>OGILVIE, James W</creator><creator>DENIS, Francis</creator><creator>WINTER, Robert B</creator><creator>WROBLEWSKI, Jill M</creator><general>Lippincott</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20080601</creationdate><title>Complications in Long Fusions to the Sacrum for Adult Scoliosis : Minimum Five-Year Analysis of Fifty Patients</title><author>WEISTROFFER, Joseph K ; PERRA, Joseph H ; LONSTEIN, John E ; SCHWENDER, James D ; GARVEY, Timothy A ; TRANSFELDT, Ensor E ; OGILVIE, James W ; DENIS, Francis ; WINTER, Robert B ; WROBLEWSKI, Jill M</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c313t-30d95b84b8ede910705b42dc68a83d1e685354bb8c760fb06d36086d6806e7543</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2008</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Biological and medical sciences</topic><topic>Cerebrospinal fluid. 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Leukoencephalitis</topic><topic>Nervous system (semeiology, syndromes)</topic><topic>Neurology</topic><topic>Pain, Postoperative - etiology</topic><topic>Pain, Postoperative - surgery</topic><topic>Pseudarthrosis - diagnostic imaging</topic><topic>Pseudarthrosis - etiology</topic><topic>Radiculopathy - etiology</topic><topic>Radiography</topic><topic>Reoperation</topic><topic>Retrospective Studies</topic><topic>Sacrum - diagnostic imaging</topic><topic>Sacrum - surgery</topic><topic>Scoliosis - diagnostic imaging</topic><topic>Scoliosis - surgery</topic><topic>Spinal Fusion - adverse effects</topic><topic>Spinal Fusion - instrumentation</topic><topic>Thoracic Vertebrae - diagnostic imaging</topic><topic>Thoracic Vertebrae - surgery</topic><topic>Time Factors</topic><topic>Treatment Outcome</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>WEISTROFFER, Joseph K</creatorcontrib><creatorcontrib>PERRA, Joseph H</creatorcontrib><creatorcontrib>LONSTEIN, John E</creatorcontrib><creatorcontrib>SCHWENDER, James D</creatorcontrib><creatorcontrib>GARVEY, Timothy A</creatorcontrib><creatorcontrib>TRANSFELDT, Ensor E</creatorcontrib><creatorcontrib>OGILVIE, James W</creatorcontrib><creatorcontrib>DENIS, Francis</creatorcontrib><creatorcontrib>WINTER, Robert B</creatorcontrib><creatorcontrib>WROBLEWSKI, Jill M</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Spine (Philadelphia, Pa. 1976)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>WEISTROFFER, Joseph K</au><au>PERRA, Joseph H</au><au>LONSTEIN, John E</au><au>SCHWENDER, James D</au><au>GARVEY, Timothy A</au><au>TRANSFELDT, Ensor E</au><au>OGILVIE, James W</au><au>DENIS, Francis</au><au>WINTER, Robert B</au><au>WROBLEWSKI, Jill M</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Complications in Long Fusions to the Sacrum for Adult Scoliosis : Minimum Five-Year Analysis of Fifty Patients</atitle><jtitle>Spine (Philadelphia, Pa. 1976)</jtitle><addtitle>Spine (Phila Pa 1976)</addtitle><date>2008-06-01</date><risdate>2008</risdate><volume>33</volume><issue>13</issue><spage>1478</spage><epage>1483</epage><pages>1478-1483</pages><issn>0362-2436</issn><eissn>1528-1159</eissn><coden>SPINDD</coden><abstract>A retrospective study of complications with minimal 5-year follow-up of 50 adults with scoliosis with fusion from T10 or higher to S1. To document the perioperative and long-term complications and instrumentation problems, and to attempt to determine variables which may influence these problems. It is not a study of curve correction, balance, or functional outcome. Several previous studies from this and other centers have shown a relatively high complication rate for this select group of patients. Various fusion techniques (anterior, posterior, autograft, allograft), various instrumentation techniques, and various immobilization techniques have created confusion as to the best methodology to employ. Minimal 2-year follow-ups have been standard, but longer follow-ups have shown additional problems. The study cohort consisted of 50 adult patients from a single center who had undergone corrective scoliosis surgery from T10 or higher to the sacrum and who had at least a 5-year minimum follow-up. The mean age was 54 years (range, 18-72), and the mean follow-up was 9.7 years (range, 5-26). All radiographs, office charts, and hospital charts were combed by an independent investigator for complications, which were divided into major and minor, as well as early, intermediate and late. The curvature values and corrections were the subject of a different article, and were not included in this study. There were no deaths or spinal cord injuries. Six patients had nerve root complications, 4 of which totally recovered. Pseudarthrosis was seen in 24% of the patients, only 25% of which were detected within the 2-year follow-up period. Pseudarthrosis was most common at the lumbosacral level. There was no statistical difference in the pseudarthrosis rate between patients with sacral-only fixation versus iliac fixation. Painful implants requiring removal were noted in 11 of the 50 patients. Long fusions to the sacrum in adults with scoliosis continue to have a high complication rate. As compared to the original publications in the 1980s (Kostuik and Hall, Spine 1983;8:489-500; Balderston et al, Spine 1986;11:824-9) the more recent articles have shown a reduction, but not elimination of the pseudarthrosis problem using segmental instrumentation and anterior fusion of the lumbar spine coupled with structural interbody grafting at L4-L5 and L5-S1. Two-year follow-up is inadequate as pseudarthrosis and painful implants often are detected later. Only 3 of the 12 patients with pseudarthrosis were detected within the first 2 years after surgery.</abstract><cop>Philadelphia, PA</cop><cop>Hagerstown, MD</cop><pub>Lippincott</pub><pmid>18520944</pmid><doi>10.1097/BRS.0b013e3181753c53</doi><tpages>6</tpages></addata></record>
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ispartof Spine (Philadelphia, Pa. 1976), 2008-06, Vol.33 (13), p.1478-1483
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subjects Adult
Aged
Biological and medical sciences
Cerebrospinal fluid. Meninges. Spinal cord
Device Removal
Follow-Up Studies
Humans
Lumbar Vertebrae - diagnostic imaging
Lumbar Vertebrae - surgery
Medical sciences
Middle Aged
Multiple sclerosis and variants. Guillain barré syndrome and other inflammatory polyneuropathies. Leukoencephalitis
Nervous system (semeiology, syndromes)
Neurology
Pain, Postoperative - etiology
Pain, Postoperative - surgery
Pseudarthrosis - diagnostic imaging
Pseudarthrosis - etiology
Radiculopathy - etiology
Radiography
Reoperation
Retrospective Studies
Sacrum - diagnostic imaging
Sacrum - surgery
Scoliosis - diagnostic imaging
Scoliosis - surgery
Spinal Fusion - adverse effects
Spinal Fusion - instrumentation
Thoracic Vertebrae - diagnostic imaging
Thoracic Vertebrae - surgery
Time Factors
Treatment Outcome
title Complications in Long Fusions to the Sacrum for Adult Scoliosis : Minimum Five-Year Analysis of Fifty Patients
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