Positive serum crossmatch as predictor for graft failure in HLA-mismatched allogeneic blood stem cell transplantation

Evaluation of patient sera for complement-fixing anti-donor antibodies (serum crossmatch [XM]) before allogeneic blood stem cell transplantation (BSCT) is routine in most centers. However, in contrast to kidney transplantation, the predictive value of a positive XM for outcome of BSCT is still uncle...

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Veröffentlicht in:	Transplantation 2002-04, Vol.73 (8), p.1280-1285
Hauptverfasser:	OTTINGER, Hellmut D, REBMANN, Vera, PFEIFFER, Kerstin A, BEELEN, Dietrich W, KREMENS, Bernhard, RUNDE, Volker, SCHAEFER, Ulrich W, GROSSE-WILDE, Hans
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Biological and medical sciences Blood Group Incompatibility Bone marrow, stem cells transplantation. Graft versus host reaction Child Child, Preschool Female Graft Survival - immunology Hematopoietic Stem Cell Transplantation - methods Hematopoietic Stem Cell Transplantation - mortality Histocompatibility Testing - methods HLA Antigens - immunology Humans Immunophenotyping Lymphocyte Culture Test, Mixed Male Medical sciences Middle Aged Predictive Value of Tests Survival Rate Transfusions. Complications. Transfusion reactions. Cell and gene therapy Treatment Failure
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