Cognitive and Behavioural Effects of Genetic Testing for Thrombophilia
Very few studies have examined the impact of genetic testing for thrombophilia on health behaviours, perceptions of control over risk factors for venous thromboembolism, or health services utilization. Through a postal questionnaire we compared first degree relatives with thrombophilia (carriers) mo...
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| Veröffentlicht in: | Journal of genetic counseling 2008-06, Vol.17 (3), p.288-296 |
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| creator | Heshka, J. Palleschi, C. Wilson, B. Brehaut, J. Rutberg, J. Etchegary, H. Langlois, N. Rodger, M. Wells, P. S. |
| description | Very few studies have examined the impact of genetic testing for thrombophilia on health behaviours, perceptions of control over risk factors for venous thromboembolism, or health services utilization. Through a postal questionnaire we compared first degree relatives with thrombophilia (carriers) most of whom had received counseling, to those without (non-carriers) with respect to: (a) perceived causes of venous thromboembolism; (b) perceived control; (c) health behaviour changes; and (d) use of health care services. 44/51 for carriers and 26/47 for non-carriers completed questionnaires. Carriers were more likely to believe their risk of venous thromboembolism ‘is a little higher’ or ‘much higher’ than average (
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| doi_str_mv | 10.1007/s10897-008-9148-1 |
| format | Article |
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p
< 0.001) but some continued to believe their risk ‘is the same as’ or ‘lower than’ average. 16%–32% of carriers did not recognize major risk factors. Stress, worry, or depression, negative attitude, and over-exertion were over-interpreted as risks. 37.2% did not appreciate that thrombophilia increases risk. Behaviour changes were uncommon. There is a need for research on education and strategies to improve knowledge in thrombophilia carriers.</description><identifier>ISSN: 1059-7700</identifier><identifier>EISSN: 1573-3599</identifier><identifier>DOI: 10.1007/s10897-008-9148-1</identifier><identifier>PMID: 18288592</identifier><language>eng</language><publisher>Boston: Springer US</publisher><subject>Behaviour change ; Biomedical and Life Sciences ; Biomedicine ; Blood clots ; Blood diseases ; Clinical Psychology ; Cognition ; Counseling ; Cross-Sectional Studies ; Education ; Ethics ; Genetic testing ; Genetic Testing - psychology ; Gynecology ; Human Genetics ; Humans ; Original Research ; Public Health ; Questionnaires ; Risk factors ; Risk perception ; Survey ; Surveys and Questionnaires ; Thrombophilia ; Thrombophilia - diagnosis ; Thrombophilia - genetics ; Venous thromboembolism</subject><ispartof>Journal of genetic counseling, 2008-06, Vol.17 (3), p.288-296</ispartof><rights>National Society of Genetic Counselors, Inc. 2008</rights><rights>2008 National Society of Genetic Counselors, Inc.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4068-a94ac471820252556defb7154b8e021ed8a87834f6af1065f06797b15af8795a3</citedby><cites>FETCH-LOGICAL-c4068-a94ac471820252556defb7154b8e021ed8a87834f6af1065f06797b15af8795a3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s10897-008-9148-1$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s10897-008-9148-1$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,776,780,1411,12826,27903,27904,30978,41467,42536,45553,45554,51297</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/18288592$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Heshka, J.</creatorcontrib><creatorcontrib>Palleschi, C.</creatorcontrib><creatorcontrib>Wilson, B.</creatorcontrib><creatorcontrib>Brehaut, J.</creatorcontrib><creatorcontrib>Rutberg, J.</creatorcontrib><creatorcontrib>Etchegary, H.</creatorcontrib><creatorcontrib>Langlois, N.</creatorcontrib><creatorcontrib>Rodger, M.</creatorcontrib><creatorcontrib>Wells, P. S.</creatorcontrib><title>Cognitive and Behavioural Effects of Genetic Testing for Thrombophilia</title><title>Journal of genetic counseling</title><addtitle>J Genet Counsel</addtitle><addtitle>J Genet Couns</addtitle><description>Very few studies have examined the impact of genetic testing for thrombophilia on health behaviours, perceptions of control over risk factors for venous thromboembolism, or health services utilization. Through a postal questionnaire we compared first degree relatives with thrombophilia (carriers) most of whom had received counseling, to those without (non-carriers) with respect to: (a) perceived causes of venous thromboembolism; (b) perceived control; (c) health behaviour changes; and (d) use of health care services. 44/51 for carriers and 26/47 for non-carriers completed questionnaires. Carriers were more likely to believe their risk of venous thromboembolism ‘is a little higher’ or ‘much higher’ than average (
p
< 0.001) but some continued to believe their risk ‘is the same as’ or ‘lower than’ average. 16%–32% of carriers did not recognize major risk factors. Stress, worry, or depression, negative attitude, and over-exertion were over-interpreted as risks. 37.2% did not appreciate that thrombophilia increases risk. Behaviour changes were uncommon. There is a need for research on education and strategies to improve knowledge in thrombophilia carriers.</description><subject>Behaviour change</subject><subject>Biomedical and Life Sciences</subject><subject>Biomedicine</subject><subject>Blood clots</subject><subject>Blood diseases</subject><subject>Clinical Psychology</subject><subject>Cognition</subject><subject>Counseling</subject><subject>Cross-Sectional Studies</subject><subject>Education</subject><subject>Ethics</subject><subject>Genetic testing</subject><subject>Genetic Testing - psychology</subject><subject>Gynecology</subject><subject>Human Genetics</subject><subject>Humans</subject><subject>Original Research</subject><subject>Public Health</subject><subject>Questionnaires</subject><subject>Risk factors</subject><subject>Risk perception</subject><subject>Survey</subject><subject>Surveys and Questionnaires</subject><subject>Thrombophilia</subject><subject>Thrombophilia - diagnosis</subject><subject>Thrombophilia - genetics</subject><subject>Venous thromboembolism</subject><issn>1059-7700</issn><issn>1573-3599</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2008</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>7QJ</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><recordid>eNqFkU9LAzEQxYMo_v8AXmTx4G11JptskqMWrYrgpZ5Ddpu0ke2mJq3itzdlC4IgnjKH33uZN4-QM4QrBBDXCUEqUQLIUiGTJe6QQ-SiKiuu1G6egatSCIADcpTSGwAoyXGfHKCkUnJFD8n9KMx6v_IftjD9tLi1c_PhwzqarrhzzrarVARXjG1vV74tJjatfD8rXIjFZB7DognLue-8OSF7znTJnm7fY_J6fzcZPZTPL-PH0c1z2TKoZWkUMy0T-XugnHJeT61rBHLWSAsU7VQaKWTFXG0cQs0d1EKJBrlxUihuqmNyOfguY3hf5230wqfWdp3pbVgnLbCu6pzyX5BujqEqlcGLX-Bbjt_nEJqirBmTVGQIB6iNIaVonV5GvzDxSyPoTRV6qELnKvSmCo1Zc741XjcLO_1RbG-fATEAn76zX_876qfxiEEWZyUdlCmL-pmNPzv_vc83q3iiBQ</recordid><startdate>200806</startdate><enddate>200806</enddate><creator>Heshka, J.</creator><creator>Palleschi, C.</creator><creator>Wilson, B.</creator><creator>Brehaut, J.</creator><creator>Rutberg, J.</creator><creator>Etchegary, H.</creator><creator>Langlois, N.</creator><creator>Rodger, M.</creator><creator>Wells, P. S.</creator><general>Springer US</general><general>Blackwell Publishing Ltd</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>0-V</scope><scope>3V.</scope><scope>7QJ</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>88G</scope><scope>8AO</scope><scope>8FD</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>ALSLI</scope><scope>AN0</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>HEHIP</scope><scope>K9.</scope><scope>KB0</scope><scope>LK8</scope><scope>M0S</scope><scope>M1P</scope><scope>M2M</scope><scope>M2S</scope><scope>M7P</scope><scope>NAPCQ</scope><scope>P64</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>PSYQQ</scope><scope>Q9U</scope><scope>RC3</scope><scope>7X8</scope></search><sort><creationdate>200806</creationdate><title>Cognitive and Behavioural Effects of Genetic Testing for Thrombophilia</title><author>Heshka, J. ; Palleschi, C. ; Wilson, B. ; Brehaut, J. ; Rutberg, J. ; Etchegary, H. ; Langlois, N. ; Rodger, M. ; Wells, P. 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S.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Cognitive and Behavioural Effects of Genetic Testing for Thrombophilia</atitle><jtitle>Journal of genetic counseling</jtitle><stitle>J Genet Counsel</stitle><addtitle>J Genet Couns</addtitle><date>2008-06</date><risdate>2008</risdate><volume>17</volume><issue>3</issue><spage>288</spage><epage>296</epage><pages>288-296</pages><issn>1059-7700</issn><eissn>1573-3599</eissn><abstract>Very few studies have examined the impact of genetic testing for thrombophilia on health behaviours, perceptions of control over risk factors for venous thromboembolism, or health services utilization. Through a postal questionnaire we compared first degree relatives with thrombophilia (carriers) most of whom had received counseling, to those without (non-carriers) with respect to: (a) perceived causes of venous thromboembolism; (b) perceived control; (c) health behaviour changes; and (d) use of health care services. 44/51 for carriers and 26/47 for non-carriers completed questionnaires. Carriers were more likely to believe their risk of venous thromboembolism ‘is a little higher’ or ‘much higher’ than average (
p
< 0.001) but some continued to believe their risk ‘is the same as’ or ‘lower than’ average. 16%–32% of carriers did not recognize major risk factors. Stress, worry, or depression, negative attitude, and over-exertion were over-interpreted as risks. 37.2% did not appreciate that thrombophilia increases risk. Behaviour changes were uncommon. There is a need for research on education and strategies to improve knowledge in thrombophilia carriers.</abstract><cop>Boston</cop><pub>Springer US</pub><pmid>18288592</pmid><doi>10.1007/s10897-008-9148-1</doi><tpages>9</tpages><oa>free_for_read</oa></addata></record> |
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| subjects | Behaviour change Biomedical and Life Sciences Biomedicine Blood clots Blood diseases Clinical Psychology Cognition Counseling Cross-Sectional Studies Education Ethics Genetic testing Genetic Testing - psychology Gynecology Human Genetics Humans Original Research Public Health Questionnaires Risk factors Risk perception Survey Surveys and Questionnaires Thrombophilia Thrombophilia - diagnosis Thrombophilia - genetics Venous thromboembolism |
| title | Cognitive and Behavioural Effects of Genetic Testing for Thrombophilia |
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