Pilomatrix carcinoma with lymph node and pulmonary metastasis: Report of a case arising on the knee

A 58-year-old woman presented with a pilomatrix carcinoma on the right knee. The tumor developed at the site of a previous lesion that had been present since she was 30 years old. Histologic study showed the presence of basaloid cells with numerous atypical mitoses, shadow cells, and calcification....

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Veröffentlicht in:The American journal of dermatopathology 2002-04, Vol.24 (2), p.139-143
Hauptverfasser: DE GALVEZ-ARANDA, Maria Victoria, HERRERA-CEBALLOS, Enrique, SANCHEZ-SANCHEZ, Purificacion, BOSCH-GARCIA, Ricardo Juan, MATILLA-VICENTE, Alfredo
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container_end_page 143
container_issue 2
container_start_page 139
container_title The American journal of dermatopathology
container_volume 24
creator DE GALVEZ-ARANDA, Maria Victoria
HERRERA-CEBALLOS, Enrique
SANCHEZ-SANCHEZ, Purificacion
BOSCH-GARCIA, Ricardo Juan
MATILLA-VICENTE, Alfredo
description A 58-year-old woman presented with a pilomatrix carcinoma on the right knee. The tumor developed at the site of a previous lesion that had been present since she was 30 years old. Histologic study showed the presence of basaloid cells with numerous atypical mitoses, shadow cells, and calcification. After several surgical excisions, the tumor mass infiltrated the subcutaneous tissue, muscle, and bone, resulting in inguinal lymph node and pulmonary metastasis. We also review the literature and comment on the histopathologic differences from other cutaneous tumors.
doi_str_mv 10.1097/00000372-200204000-00006
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source Journals@Ovid Ovid Autoload; MEDLINE
subjects Biological and medical sciences
Calcinosis - pathology
Dermatology
Female
Hair Diseases - pathology
Hair Diseases - surgery
Humans
Knee - pathology
Lung Neoplasms - secondary
Lymph Nodes - pathology
Lymphatic Metastasis
Medical sciences
Middle Aged
Neoplasm Recurrence, Local
Pilomatrixoma - secondary
Pilomatrixoma - surgery
Skin Neoplasms - pathology
Skin Neoplasms - surgery
Tumors of the skin and soft tissue. Premalignant lesions
title Pilomatrix carcinoma with lymph node and pulmonary metastasis: Report of a case arising on the knee
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