Structures of the Human Rad17-Replication Factor C and Checkpoint Rad 9-1-1 Complexes Visualized by Glycerol Spray/Low Voltage Microscopy

Human checkpoint Rad proteins are thought to function as damage sensors in the DNA damage checkpoint response pathway. The checkpoint proteins hRad9, hHus1, and hRad1 have limited homology to the replication processivity factor proliferating cell nuclear antigen (PCNA), and hRad17 has homology to re...

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Veröffentlicht in:	The Journal of biological chemistry 2002-05, Vol.277 (18), p.15233-15236
Hauptverfasser:	Griffith, Jack D., Lindsey-Boltz, Laura A., Sancar, Aziz
Format:	Artikel
Sprache:	eng
Schlagworte:	Cell Cycle Proteins - chemistry Cell Cycle Proteins - ultrastructure DNA-Binding Proteins - chemistry DNA-Binding Proteins - ultrastructure Glycerol Humans Microscopy, Electron Proliferating Cell Nuclear Antigen - chemistry Proliferating Cell Nuclear Antigen - ultrastructure Rad17 protein Rad51 protein ras Proteins Recombinant Proteins - chemistry Recombinant Proteins - ultrastructure replication factor C Replication Protein C Transfection
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