Role of protease-activated receptors in inflammatory responses, innate and adaptive immunity

Serine proteases are well known as enzymes involved in digestion of dietary proteins, blood coagulation, and homeostasis. Only recent groundbreaking studies revealed a novel role of serine proteases as signaling molecules acting via protease‐activated receptors (PARs). Important effects of PAR activ...

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Veröffentlicht in:	Journal of leukocyte biology 2008-06, Vol.83 (6), p.1309-1322
Hauptverfasser:	Shpacovitch, V., Feld, M., Hollenberg, M. D., Luger, T. A., Steinhoff, M.
Format:	Artikel
Sprache:	eng
Schlagworte:	allergy Animals Asthma - etiology Basophils - physiology Dendritic Cells - physiology Eosinophils - physiology Humans Immunity, Innate infectious diseases Inflammation - etiology leukocytes Lymphocytes - physiology Mast Cells - physiology Monocytes - physiology Neutrophils - physiology proteolytic enzymes Receptors, Proteinase-Activated - physiology
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