Associations of human leukocyte antigen DRB with resistance or susceptibility to HIV-1 infection in the Pumwani Sex Worker Cohort

A group of commercial sex workers in the Pumwani Sex Worker Cohort, established in 1985 in Nairobi, Kenya, remain HIV-1 uninfected despite heavy exposure to HIV-1 through active sex work. Previous studies showed that this resistance is associated with a strong CD4+ T-cell response, which suggested t...

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Veröffentlicht in:	AIDS (London) 2008-05, Vol.22 (9), p.1029-1038
Hauptverfasser:	LACAP, Philip A, HUNTINGTON, Janis D, MA LUO, NAGELKERKE, Nico J. D, BIELAWNY, Thomas, KIMANI, Joshua, WACHIHI, Charles, NGUGI, Elizabeth N, PLUMMER, Francis A
Format:	Artikel
Sprache:	eng
Schlagworte:	AIDS/HIV Alleles Biological and medical sciences CD4-Positive T-Lymphocytes Cohort Studies Female Genetic Predisposition to Disease Haplotypes HIV Infections - genetics HIV Infections - immunology HIV-1 - immunology HLA-DR Antigens - genetics HLA-DRB1 Chains Human immunodeficiency virus 1 Human viral diseases Humans Immunodeficiencies Immunodeficiencies. Immunoglobulinopathies Immunopathology Infectious diseases Kenya Medical sciences Sex Work Viral diseases Viral diseases of the lymphoid tissue and the blood. Aids
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