Developmentally-related candidate retinoic acid target genes regulated early during neuronal differentiation of human embryonal carcinoma

Embryonal carcinoma is a model of embryonic development as well as tumor cell differentiation. In response to all-trans retinoic acid (RA), the human embryonal carcinoma (EC) cell line, NT2/D1, differentiates toward a neuronal lineage with associated loss of cell growth and tumorigenicity. Through t...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Oncogene 2002-04, Vol.21 (18), p.2880-2889
Hauptverfasser:	FREEMANTLE, Sarah J, KERLEY, Joanna S, OLSEN, Shannon L, GROSS, Robert H, SPINELLA, Michael J
Format:	Artikel
Sprache:	eng
Schlagworte:	Acids Biological and medical sciences Biotechnology Cancer Carcinoma, Embryonal Cell adhesion Cell Differentiation Cell growth Connective tissue growth factor Cytoskeleton DNA microarrays Embryogenesis Follistatin Frizzled protein Frizzled-related protein Frizzled-related protein 1 Fundamental and applied biological sciences. Psychology Gene Expression Regulation, Developmental Gene therapy Genes Health. Pharmaceutical industry Humans Industrial applications and implications. Economical aspects Insulin-like growth factor-binding protein 3 Insulin-like growth factor-binding protein 6 Insulin-like growth factors Intracellular signalling Neurons - cytology Neurons - drug effects Neurotrophin 2 Oligonucleotide Array Sequence Analysis Protein turnover Retinoic acid RNA processing Stem cells Toxicology Tretinoin - pharmacology Tumor Cells, Cultured Tumorigenesis Tumorigenicity Tumors Wnt protein
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!