Hydrophilic interaction liquid chromatography method for the determination of ascorbic acid

Hydrophilic interaction liquid chromatography (HILIC) method using internal standard for the determination and stability study of ascorbic acid was developed. HILIC method was very fast and simple using the following analytical conditions: ZIC HILIC (150x2.1 mm, 3.5 μm) chromatographic column and mo...

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Veröffentlicht in:	Journal of separation science 2008-05, Vol.31 (9), p.1634-1644
Hauptverfasser:	Nováková, Lucie, Solichová, Dagmar, Pavlovičová, Soňa, Solich, Petr
Format:	Artikel
Sprache:	eng
Schlagworte:	Ascorbic acid Ascorbic Acid - analysis Ascorbic Acid - metabolism Ascorbic Acid - standards Chlorogenic Acid - analysis Chlorogenic Acid - standards Chromatography, High Pressure Liquid - methods Chromatography, Liquid - methods Chromatography, Liquid - standards Drug Stability HILIC Humans Hydrogen-Ion Concentration Indicators and Reagents o-phosphoric acid Oxalic acid Oxygen Phase Transition Reference Standards Solvents Spectrophotometry, Ultraviolet Stability Temperature Vitamins
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