Design and Synthesis of Chemiluminescent Probes for the Detection of Cholinesterase Activity

Acetylcholinesterase is one of the most widely used and studied enzymes. Not only does this enzyme regulate neurotransmission (and thus play a key role in neurodegenerative processes) but it is also a prime target for pest control agents and warfare agents. Above all, due to its particularly high tu...

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Veröffentlicht in:	Journal of the American Chemical Society 2002-05, Vol.124 (17), p.4874-4880
Hauptverfasser:	Sabelle, Stéphane, Renard, Pierre-Yves, Pecorella, Karine, de Suzzoni-Dézard, Sophie, Créminon, Christophe, Grassi, Jacques, Mioskowski, Charles
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetylcholinesterase - analysis Acetylcholinesterase - metabolism Analytical, structural and metabolic biochemistry Animals Biological and medical sciences Disulfides - chemical synthesis Disulfides - chemistry Electrophorus - metabolism Enzymes and enzyme inhibitors Fundamental and applied biological sciences. Psychology General aspects, investigation methods Heterocyclic Compounds - chemical synthesis Heterocyclic Compounds - chemistry Luminescent Measurements
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