Novel autoantigens recognized by CSF IgG from Hashimoto's encephalitis revealed by a proteomic approach

Abstract To identify the target of IgG autoimmune response in Hashimoto's encephalopathy (HE), we studied the binding of IgG present in serum and cerebro-spinal fluid (CSF) from six patients with HE and 15 controls to human central nervous system (CNS) white matter antigens by 2D-PAGE and immun...

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Veröffentlicht in:	Journal of neuroimmunology 2008-05, Vol.196 (1), p.153-158
Hauptverfasser:	Gini, Beatrice, Laura, Lovato, Riccardo, Cianti, Laura, Cecotti, Marconi, Silvia, Anghileri, Elena, Alessandro, Armini, Giuseppe, Moretto, Luca, Bini, Franco, Ferracci, Bruno, Bonetti
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged AKRIAI Aldehyde Reductase - metabolism Allergy and Immunology Amidohydrolases - metabolism Autoantibodies Autoantigens - cerebrospinal fluid Autoantigens - immunology Blood Vessels - metabolism DDAHI Electrophoresis, Gel, Two-Dimensional - methods Female Hashimoto Disease - cerebrospinal fluid Hashimoto Disease - immunology Hashimoto Disease - pathology Hashimoto's encephalitis Humans Immunoglobulin G - cerebrospinal fluid Male Mass Spectrometry - methods Middle Aged Neurology Proteomics Proteomics - methods
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