Prediction of arterial oxygen tension during one-lung ventilation: Analysis of preoperative and intraoperative variables
Objective: To determine whether currently available preoperative and intraoperative variables related to arterial oxygen tension (PaO2) can be used as predictors for low PaO2 during one-lung ventilation (OLV). Design: A prospective cohort study. Setting: Primary university hospital. Participants: Ad...
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| Veröffentlicht in: | Journal of cardiothoracic and vascular anesthesia 2002-04, Vol.16 (2), p.199-203 |
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| container_title | Journal of cardiothoracic and vascular anesthesia |
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| creator | Guenoun, Thierry Journois, Didier Silleran-Chassany, Jacqueline Frappier, Jerôme D'Attellis, Nicola Salem, Antoinette Safran, Denis |
| description | Objective: To determine whether currently available preoperative and intraoperative variables related to arterial oxygen tension (PaO2) can be used as predictors for low PaO2 during one-lung ventilation (OLV). Design: A prospective cohort study. Setting: Primary university hospital. Participants: Adult patients (n = 92) undergoing thoracic surgery requiring OLV. Interventions: Preoperative and intraoperative data, including past medical history, physical examination, and usual preoperative and intraoperative tests, were collected and used as explanatory variables for PaO2 during OLV by univariate and multivariate analysis. A stepwise logistic regression including the same independent variables was used to identify patients who should be expected to develop arterial hypoxemia (PaO2 |
| doi_str_mv | 10.1053/jcan.2002.31067 |
| format | Article |
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Design: A prospective cohort study. Setting: Primary university hospital. Participants: Adult patients (n = 92) undergoing thoracic surgery requiring OLV. Interventions: Preoperative and intraoperative data, including past medical history, physical examination, and usual preoperative and intraoperative tests, were collected and used as explanatory variables for PaO2 during OLV by univariate and multivariate analysis. A stepwise logistic regression including the same independent variables was used to identify patients who should be expected to develop arterial hypoxemia (PaO2 <70 mmHg). Arterial blood gas samples were analyzed 15 minutes after the onset of OLV and after thoracotomy to determine the lowest PaO2 value during OLV. Measurements and Main Results: Preoperative (age, hematocrit, relative perfusion of the nondependent lung) and intraoperative (PaO2 during 2-lung ventilation and mean arterial pressure at the lowest PaO2) variables were identified as independent factors affecting PaO2 in OLV. PaO2 during 2-lung ventilation was the only independent variable accounting for arterial hypoxemia when multivariate logistic regression was performed. Conclusion: The PaO2 during OLV can be predicted using routinely available preoperative and intraoperative data. From a clinical point of view, this study failed to identify patients at risk of arterial hypoxemia when OLV is instituted because mainly intraoperative independent variables are involved in the decrease of PaO2 in this situation.</description><identifier>ISSN: 1053-0770</identifier><identifier>EISSN: 1532-8422</identifier><identifier>DOI: 10.1053/jcan.2002.31067</identifier><identifier>PMID: 11957171</identifier><language>eng</language><publisher>Philadelphia, PA: Elsevier Inc</publisher><subject>Adult ; Aged ; Analysis of Variance ; Anesthesia ; Anesthesia depending on type of surgery ; Anesthesia, General ; Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy ; Biological and medical sciences ; Blood Pressure ; Cohort Studies ; Female ; Humans ; Male ; Medical sciences ; Middle Aged ; Multivariate Analysis ; Oxygen - blood ; Prospective Studies ; Regression Analysis ; Respiration, Artificial - methods ; Respiratory Mechanics ; Thoracic and cardiovascular surgery. Cardiopulmonary bypass ; Thoracic Surgical Procedures</subject><ispartof>Journal of cardiothoracic and vascular anesthesia, 2002-04, Vol.16 (2), p.199-203</ispartof><rights>2002 Elsevier Science (USA)</rights><rights>2002 INIST-CNRS</rights><rights>Copyright 2002, Elsevier Science (USA). All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c373t-630f3d013ffac47cfa804ff0eeecb18243efa6e7e8fe152e6829f24ec439973c3</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1053/jcan.2002.31067$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3536,27903,27904,45974</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=13621950$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/11957171$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Guenoun, Thierry</creatorcontrib><creatorcontrib>Journois, Didier</creatorcontrib><creatorcontrib>Silleran-Chassany, Jacqueline</creatorcontrib><creatorcontrib>Frappier, Jerôme</creatorcontrib><creatorcontrib>D'Attellis, Nicola</creatorcontrib><creatorcontrib>Salem, Antoinette</creatorcontrib><creatorcontrib>Safran, Denis</creatorcontrib><title>Prediction of arterial oxygen tension during one-lung ventilation: Analysis of preoperative and intraoperative variables</title><title>Journal of cardiothoracic and vascular anesthesia</title><addtitle>J Cardiothorac Vasc Anesth</addtitle><description>Objective: To determine whether currently available preoperative and intraoperative variables related to arterial oxygen tension (PaO2) can be used as predictors for low PaO2 during one-lung ventilation (OLV). Design: A prospective cohort study. Setting: Primary university hospital. Participants: Adult patients (n = 92) undergoing thoracic surgery requiring OLV. Interventions: Preoperative and intraoperative data, including past medical history, physical examination, and usual preoperative and intraoperative tests, were collected and used as explanatory variables for PaO2 during OLV by univariate and multivariate analysis. A stepwise logistic regression including the same independent variables was used to identify patients who should be expected to develop arterial hypoxemia (PaO2 <70 mmHg). Arterial blood gas samples were analyzed 15 minutes after the onset of OLV and after thoracotomy to determine the lowest PaO2 value during OLV. Measurements and Main Results: Preoperative (age, hematocrit, relative perfusion of the nondependent lung) and intraoperative (PaO2 during 2-lung ventilation and mean arterial pressure at the lowest PaO2) variables were identified as independent factors affecting PaO2 in OLV. PaO2 during 2-lung ventilation was the only independent variable accounting for arterial hypoxemia when multivariate logistic regression was performed. Conclusion: The PaO2 during OLV can be predicted using routinely available preoperative and intraoperative data. From a clinical point of view, this study failed to identify patients at risk of arterial hypoxemia when OLV is instituted because mainly intraoperative independent variables are involved in the decrease of PaO2 in this situation.</description><subject>Adult</subject><subject>Aged</subject><subject>Analysis of Variance</subject><subject>Anesthesia</subject><subject>Anesthesia depending on type of surgery</subject><subject>Anesthesia, General</subject><subject>Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy</subject><subject>Biological and medical sciences</subject><subject>Blood Pressure</subject><subject>Cohort Studies</subject><subject>Female</subject><subject>Humans</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Multivariate Analysis</subject><subject>Oxygen - blood</subject><subject>Prospective Studies</subject><subject>Regression Analysis</subject><subject>Respiration, Artificial - methods</subject><subject>Respiratory Mechanics</subject><subject>Thoracic and cardiovascular surgery. Cardiopulmonary bypass</subject><subject>Thoracic Surgical Procedures</subject><issn>1053-0770</issn><issn>1532-8422</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2002</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp1kUFr3DAQRkVpadK0596KL-3NG41kW3ZvIaRNINAckrOYlUdBQSttJXvJ_vvI3YU99TTDzJsP8cTYV-Ar4K28fDEYVoJzsZLAO_WOnUMrRd03QrwvfUFqrhQ_Y59yfuEcoG3VR3YGMLQKFJyz14dEozOTi6GKtsI0UXLoq_i6f6ZQTRTyshrn5MJzFQPVfi7NjsLkPC5nP6urgH6fXV4CtonillLZ7KjCMFYuTAlPox2W-LWn_Jl9sOgzfTnWC_b06-bx-ra-__P77vrqvjZSyanuJLdy5CCtRdMoY7HnjbWciMwaetFIstiRot4StIK6XgxWNGQaOQxKGnnBfhxytyn-nSlPeuOyIe8xUJyzVtABKK4KeHkATYo5J7J6m9wG014D14tJvcjWi2z9T3a5-HaMntcbGk_80W4Bvh8BzAa9TRiMyydOdqKgvHDDgaMiYuco6WwcBVN-JpGZ9Bjdfx_xBvjonqw</recordid><startdate>20020401</startdate><enddate>20020401</enddate><creator>Guenoun, Thierry</creator><creator>Journois, Didier</creator><creator>Silleran-Chassany, Jacqueline</creator><creator>Frappier, Jerôme</creator><creator>D'Attellis, Nicola</creator><creator>Salem, Antoinette</creator><creator>Safran, Denis</creator><general>Elsevier Inc</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20020401</creationdate><title>Prediction of arterial oxygen tension during one-lung ventilation: Analysis of preoperative and intraoperative variables</title><author>Guenoun, Thierry ; Journois, Didier ; Silleran-Chassany, Jacqueline ; Frappier, Jerôme ; D'Attellis, Nicola ; Salem, Antoinette ; Safran, Denis</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c373t-630f3d013ffac47cfa804ff0eeecb18243efa6e7e8fe152e6829f24ec439973c3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2002</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Analysis of Variance</topic><topic>Anesthesia</topic><topic>Anesthesia depending on type of surgery</topic><topic>Anesthesia, General</topic><topic>Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy</topic><topic>Biological and medical sciences</topic><topic>Blood Pressure</topic><topic>Cohort Studies</topic><topic>Female</topic><topic>Humans</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Multivariate Analysis</topic><topic>Oxygen - blood</topic><topic>Prospective Studies</topic><topic>Regression Analysis</topic><topic>Respiration, Artificial - methods</topic><topic>Respiratory Mechanics</topic><topic>Thoracic and cardiovascular surgery. Cardiopulmonary bypass</topic><topic>Thoracic Surgical Procedures</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Guenoun, Thierry</creatorcontrib><creatorcontrib>Journois, Didier</creatorcontrib><creatorcontrib>Silleran-Chassany, Jacqueline</creatorcontrib><creatorcontrib>Frappier, Jerôme</creatorcontrib><creatorcontrib>D'Attellis, Nicola</creatorcontrib><creatorcontrib>Salem, Antoinette</creatorcontrib><creatorcontrib>Safran, Denis</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of cardiothoracic and vascular anesthesia</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Guenoun, Thierry</au><au>Journois, Didier</au><au>Silleran-Chassany, Jacqueline</au><au>Frappier, Jerôme</au><au>D'Attellis, Nicola</au><au>Salem, Antoinette</au><au>Safran, Denis</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Prediction of arterial oxygen tension during one-lung ventilation: Analysis of preoperative and intraoperative variables</atitle><jtitle>Journal of cardiothoracic and vascular anesthesia</jtitle><addtitle>J Cardiothorac Vasc Anesth</addtitle><date>2002-04-01</date><risdate>2002</risdate><volume>16</volume><issue>2</issue><spage>199</spage><epage>203</epage><pages>199-203</pages><issn>1053-0770</issn><eissn>1532-8422</eissn><abstract>Objective: To determine whether currently available preoperative and intraoperative variables related to arterial oxygen tension (PaO2) can be used as predictors for low PaO2 during one-lung ventilation (OLV). Design: A prospective cohort study. Setting: Primary university hospital. Participants: Adult patients (n = 92) undergoing thoracic surgery requiring OLV. Interventions: Preoperative and intraoperative data, including past medical history, physical examination, and usual preoperative and intraoperative tests, were collected and used as explanatory variables for PaO2 during OLV by univariate and multivariate analysis. A stepwise logistic regression including the same independent variables was used to identify patients who should be expected to develop arterial hypoxemia (PaO2 <70 mmHg). Arterial blood gas samples were analyzed 15 minutes after the onset of OLV and after thoracotomy to determine the lowest PaO2 value during OLV. Measurements and Main Results: Preoperative (age, hematocrit, relative perfusion of the nondependent lung) and intraoperative (PaO2 during 2-lung ventilation and mean arterial pressure at the lowest PaO2) variables were identified as independent factors affecting PaO2 in OLV. PaO2 during 2-lung ventilation was the only independent variable accounting for arterial hypoxemia when multivariate logistic regression was performed. Conclusion: The PaO2 during OLV can be predicted using routinely available preoperative and intraoperative data. From a clinical point of view, this study failed to identify patients at risk of arterial hypoxemia when OLV is instituted because mainly intraoperative independent variables are involved in the decrease of PaO2 in this situation.</abstract><cop>Philadelphia, PA</cop><pub>Elsevier Inc</pub><pmid>11957171</pmid><doi>10.1053/jcan.2002.31067</doi><tpages>5</tpages></addata></record> |
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| subjects | Adult Aged Analysis of Variance Anesthesia Anesthesia depending on type of surgery Anesthesia, General Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Biological and medical sciences Blood Pressure Cohort Studies Female Humans Male Medical sciences Middle Aged Multivariate Analysis Oxygen - blood Prospective Studies Regression Analysis Respiration, Artificial - methods Respiratory Mechanics Thoracic and cardiovascular surgery. Cardiopulmonary bypass Thoracic Surgical Procedures |
| title | Prediction of arterial oxygen tension during one-lung ventilation: Analysis of preoperative and intraoperative variables |
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