Follistatin-related protein and follistatin differentially neutralize endogenous vs. exogenous activin

Follistatin-related protein (FSRP) is a new addition to the expanding follistatin (FS)-related gene family whose members contain at least one conserved 10-cysteine follistatin domain. In contrast to other members of this family, FSRP and follistatin also share a common exon/intron domain structure,...

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Veröffentlicht in:	Endocrinology (Philadelphia) 2002-05, Vol.143 (5), p.1613-1624
Hauptverfasser:	Sidis, Yisrael, Tortoriello, Drew V, Holmes, William E, Pan, Yang, Keutmann, Henry T, Schneyer, Alan L
Format:	Artikel
Sprache:	eng
Schlagworte:	Activin Receptors - antagonists & inhibitors Activins - antagonists & inhibitors Activins - pharmacology Amino Acid Sequence Animals Binding, Competitive - drug effects Cell Line COS Cells Follistatin Follistatin-Related Proteins Glycoproteins - pharmacology Heparin - metabolism Humans Ligands Luciferases - biosynthesis Luciferases - genetics Male Mice Molecular Sequence Data Pituitary Gland - drug effects Pituitary Gland - metabolism Pituitary Neoplasms - metabolism Protein Binding Proteoglycans - metabolism Rats Rats, Sprague-Dawley Recombinant Proteins - pharmacology
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