The role of Rho GTPases in disease development

The functionality and efficacy of Rho GTPase signaling is pivotal for a plethora of biological processes. Due to the integral nature of these molecules, the dysregulation of their activities can result in diverse aberrant phenotypes. Dysregulation can, as will be described below, be based on an alte...

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Veröffentlicht in:	Gene 2002-03, Vol.286 (2), p.155-174
Hauptverfasser:	Boettner, Benjamin, Van Aelst, Linda
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cancer Deafness - genetics Disease Humans Neoplasms - genetics Neurodegenerative Diseases - genetics Neurological disorder rho GTP-Binding Proteins - genetics rho GTP-Binding Proteins - physiology Rho GTPase Signaling Tangier Disease - genetics Wiskott-Aldrich Syndrome - genetics
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