Increased Levels of Antimicrobial Peptides in Tracheal Aspirates of Newborn Infants during Infection

Pneumonia and systemic infection are common in premature infants. The antimicrobial peptides human beta-defensin 1 and 2 (hBD-1 and hBD-2) and the cathelicidin LL-37/hCAP-18 are effector molecules of the innate respiratory immune system. It is unknown whether these host defense substances are produc...

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Veröffentlicht in:	American journal of respiratory and critical care medicine 2002-04, Vol.165 (7), p.992-995
Hauptverfasser:	SCHALLER-BALS, SUSANNE, SCHULZE, ANDREAS, BALS, ROBERT
Format:	Artikel
Sprache:	eng
Schlagworte:	Antimicrobial Cationic Peptides - metabolism Bacterial diseases Bacterial diseases of the respiratory system beta-Defensins - metabolism Biological and medical sciences Blotting, Western Bronchoalveolar Lavage Fluid - chemistry Cathelicidins Human bacterial diseases Humans Infant, Newborn Infant, Premature, Diseases - immunology Infectious diseases Inflammation Mediators - metabolism Medical sciences Respiratory Tract Infections - immunology Systemic Inflammatory Response Syndrome - immunology Trachea - immunology
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