The Human Monocarboxylate Transporter, MCT1: Genomic Organization and Promoter Analysis

Uptake of butyrate across the colonocyte luminal membrane is mediated by the monocarboxylate transporter isoform 1 (MCT1). We have demonstrated previously that expression of human colonic MCT1 is responsive to butyrate, and that this involves the dual control of MCT1 gene transcription and stability...

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Veröffentlicht in:	Biochemical and biophysical research communications 2002-04, Vol.292 (4), p.1048-1056
Hauptverfasser:	Cuff, Mark A., Shirazi-Beechey, Soraya P.
Format:	Artikel
Sprache:	eng
Schlagworte:	3' Untranslated Regions - genetics 5' Untranslated Regions - genetics Base Sequence butyrate butyrate transport Cell Line Colon Exons gene structure Genes, Reporter Humans Intestinal Mucosa - cytology Intestinal Mucosa - metabolism Introns MCT1 MCT1 gene Molecular Sequence Data Monocarboxylate transporter Monocarboxylic Acid Transporters - biosynthesis Monocarboxylic Acid Transporters - genetics promoter Promoter Regions, Genetic Regulatory Sequences, Nucleic Acid Sequence Analysis, DNA Sequence Deletion Symporters - biosynthesis Symporters - genetics Transcription Initiation Site Transfection
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