Plasma tissue inhibitor of metalloproteinase-1 levels are elevated in essential hypertension and related to left ventricular hypertrophy

Essential hypertensive patients have an increased heart and arterial collagen concentration. Increased collagen synthesis can be assessed using procollagen III N peptide (PIIINP) and reduced collagen degradation measured using tissue inhibitor of metalloproteinase-1 (TIMP-1). Plasma TIMP-1 and PIIIN...

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Veröffentlicht in:	American journal of hypertension 2002-03, Vol.15 (3), p.269-272
Hauptverfasser:	Timms, Peter Mc.Lean, Wright, Ann, Maxwell, Paul, Campbell, Stewart, Dawnay, Anne Beatrice, Srikanthan, Vinajur
Format:	Artikel
Sprache:	eng
Schlagworte:	angiotensin II Arterial hypertension. Arterial hypotension Biological and medical sciences Blood and lymphatic vessels Cardiology. Vascular system Clinical manifestations. Epidemiology. Investigative techniques. Etiology Essential hypertension Female Humans Hypertension - blood Hypertrophy, Left Ventricular - complications LVH Male Medical sciences Middle Aged Peptide Fragments - blood PIIINP Procollagen - blood TIMP-1 Tissue Inhibitor of Metalloproteinase-1 - blood
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