Innovations in pancreas transplantation
Pancreas transplantation is currently the curative treatment for type 1 diabetes mellitus. It aims at providing physiological insulin replacement therapy in type 1 diabetes mellitus. The goal is thereby also to prevent secondary complications of diabetes. Long term control of glucose metabolism has...
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Veröffentlicht in: | Saudi medical journal 2002-03, Vol.23 (3), p.265-271 |
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container_title | Saudi medical journal |
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creator | AL-SHURAFA, Haider A JAWDAT, Muaffak T BASSAS, Atef F ROGIERS, Xavier C BECHSTEIN, Wolf O |
description | Pancreas transplantation is currently the curative treatment for type 1 diabetes mellitus. It aims at providing physiological insulin replacement therapy in type 1 diabetes mellitus. The goal is thereby also to prevent secondary complications of diabetes. Long term control of glucose metabolism has only been achieved by pancreas transplantation. As a result of improvements in the surgical techniques and the efficacy of immunosuppression, the patient and graft survival rates have improved dramatically over the last 2 decades. As a result, pancreas transplantation, as part of simultaneous pancreas and kidney transplantation, pancreas after kidney transplantation, and exceptionally pancreas transplantation alone, became the standard therapeutic option for patients with type 1 diabetes mellitus with end-stage renal disease. In this article we review the pancreas transplantation methods, indications, techniques, and the short as well as the long outcomes of treatment. |
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It aims at providing physiological insulin replacement therapy in type 1 diabetes mellitus. The goal is thereby also to prevent secondary complications of diabetes. Long term control of glucose metabolism has only been achieved by pancreas transplantation. As a result of improvements in the surgical techniques and the efficacy of immunosuppression, the patient and graft survival rates have improved dramatically over the last 2 decades. As a result, pancreas transplantation, as part of simultaneous pancreas and kidney transplantation, pancreas after kidney transplantation, and exceptionally pancreas transplantation alone, became the standard therapeutic option for patients with type 1 diabetes mellitus with end-stage renal disease. In this article we review the pancreas transplantation methods, indications, techniques, and the short as well as the long outcomes of treatment.</description><identifier>ISSN: 0379-5284</identifier><identifier>PMID: 11938413</identifier><identifier>CODEN: SAMJDI</identifier><language>eng</language><publisher>Riyadh: Saudi Medical Journal</publisher><subject>Biological and medical sciences ; Diabetes Mellitus, Type 1 - complications ; Diabetes Mellitus, Type 1 - surgery ; Humans ; Kidney Failure, Chronic - etiology ; Kidney Failure, Chronic - surgery ; Kidney Transplantation ; Liver, biliary tract, pancreas, portal circulation, spleen ; Medical sciences ; Pancreas Transplantation - methods ; Pancreas Transplantation - trends ; Patient Selection ; Perioperative Care ; Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases ; Surgery of the digestive system ; Tissue Donors</subject><ispartof>Saudi medical journal, 2002-03, Vol.23 (3), p.265-271</ispartof><rights>2002 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=13563482$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/11938413$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>AL-SHURAFA, Haider A</creatorcontrib><creatorcontrib>JAWDAT, Muaffak T</creatorcontrib><creatorcontrib>BASSAS, Atef F</creatorcontrib><creatorcontrib>ROGIERS, Xavier C</creatorcontrib><creatorcontrib>BECHSTEIN, Wolf O</creatorcontrib><title>Innovations in pancreas transplantation</title><title>Saudi medical journal</title><addtitle>Saudi Med J</addtitle><description>Pancreas transplantation is currently the curative treatment for type 1 diabetes mellitus. It aims at providing physiological insulin replacement therapy in type 1 diabetes mellitus. The goal is thereby also to prevent secondary complications of diabetes. Long term control of glucose metabolism has only been achieved by pancreas transplantation. As a result of improvements in the surgical techniques and the efficacy of immunosuppression, the patient and graft survival rates have improved dramatically over the last 2 decades. As a result, pancreas transplantation, as part of simultaneous pancreas and kidney transplantation, pancreas after kidney transplantation, and exceptionally pancreas transplantation alone, became the standard therapeutic option for patients with type 1 diabetes mellitus with end-stage renal disease. In this article we review the pancreas transplantation methods, indications, techniques, and the short as well as the long outcomes of treatment.</description><subject>Biological and medical sciences</subject><subject>Diabetes Mellitus, Type 1 - complications</subject><subject>Diabetes Mellitus, Type 1 - surgery</subject><subject>Humans</subject><subject>Kidney Failure, Chronic - etiology</subject><subject>Kidney Failure, Chronic - surgery</subject><subject>Kidney Transplantation</subject><subject>Liver, biliary tract, pancreas, portal circulation, spleen</subject><subject>Medical sciences</subject><subject>Pancreas Transplantation - methods</subject><subject>Pancreas Transplantation - trends</subject><subject>Patient Selection</subject><subject>Perioperative Care</subject><subject>Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases</subject><subject>Surgery of the digestive system</subject><subject>Tissue Donors</subject><issn>0379-5284</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2002</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpFz01Lw0AQBuA9KLZW_4Lkop4CO7Mf2T1K8aNQ8KLnMPtRiCSbmE0E_71BKz3NYR7emfeMrbmobKnQyBW7zPmDc6E11xdsBWCFkSDW7H6XUv9FU9OnXDSpGCj5MVIuppFSHlpK0-_yip0fqM3x-jg37P3p8W37Uu5fn3fbh305oKim0gVviFfBgYUAAIgiGIjArQIrPUIU2kiFzuJyngyCckppGyrHPUoSG3b3lzuM_ecc81R3TfaxXR6J_ZzrCpQBi3yBN0c4uy6Gehibjsbv-r_aAm6PgLKn9rD08U0-OaG0kAbFD8b-VFg</recordid><startdate>20020301</startdate><enddate>20020301</enddate><creator>AL-SHURAFA, Haider A</creator><creator>JAWDAT, Muaffak T</creator><creator>BASSAS, Atef F</creator><creator>ROGIERS, Xavier C</creator><creator>BECHSTEIN, Wolf O</creator><general>Saudi Medical Journal</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>20020301</creationdate><title>Innovations in pancreas transplantation</title><author>AL-SHURAFA, Haider A ; JAWDAT, Muaffak T ; BASSAS, Atef F ; ROGIERS, Xavier C ; BECHSTEIN, Wolf O</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p237t-bdc8a07db191d111223d81e1095194c21e368452b92413a8215b5569d7b0c24a3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2002</creationdate><topic>Biological and medical sciences</topic><topic>Diabetes Mellitus, Type 1 - complications</topic><topic>Diabetes Mellitus, Type 1 - surgery</topic><topic>Humans</topic><topic>Kidney Failure, Chronic - etiology</topic><topic>Kidney Failure, Chronic - surgery</topic><topic>Kidney Transplantation</topic><topic>Liver, biliary tract, pancreas, portal circulation, spleen</topic><topic>Medical sciences</topic><topic>Pancreas Transplantation - methods</topic><topic>Pancreas Transplantation - trends</topic><topic>Patient Selection</topic><topic>Perioperative Care</topic><topic>Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases</topic><topic>Surgery of the digestive system</topic><topic>Tissue Donors</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>AL-SHURAFA, Haider A</creatorcontrib><creatorcontrib>JAWDAT, Muaffak T</creatorcontrib><creatorcontrib>BASSAS, Atef F</creatorcontrib><creatorcontrib>ROGIERS, Xavier C</creatorcontrib><creatorcontrib>BECHSTEIN, Wolf O</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>Saudi medical journal</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>AL-SHURAFA, Haider A</au><au>JAWDAT, Muaffak T</au><au>BASSAS, Atef F</au><au>ROGIERS, Xavier C</au><au>BECHSTEIN, Wolf O</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Innovations in pancreas transplantation</atitle><jtitle>Saudi medical journal</jtitle><addtitle>Saudi Med J</addtitle><date>2002-03-01</date><risdate>2002</risdate><volume>23</volume><issue>3</issue><spage>265</spage><epage>271</epage><pages>265-271</pages><issn>0379-5284</issn><coden>SAMJDI</coden><abstract>Pancreas transplantation is currently the curative treatment for type 1 diabetes mellitus. It aims at providing physiological insulin replacement therapy in type 1 diabetes mellitus. The goal is thereby also to prevent secondary complications of diabetes. Long term control of glucose metabolism has only been achieved by pancreas transplantation. As a result of improvements in the surgical techniques and the efficacy of immunosuppression, the patient and graft survival rates have improved dramatically over the last 2 decades. As a result, pancreas transplantation, as part of simultaneous pancreas and kidney transplantation, pancreas after kidney transplantation, and exceptionally pancreas transplantation alone, became the standard therapeutic option for patients with type 1 diabetes mellitus with end-stage renal disease. In this article we review the pancreas transplantation methods, indications, techniques, and the short as well as the long outcomes of treatment.</abstract><cop>Riyadh</cop><pub>Saudi Medical Journal</pub><pmid>11938413</pmid><tpages>7</tpages></addata></record> |
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subjects | Biological and medical sciences Diabetes Mellitus, Type 1 - complications Diabetes Mellitus, Type 1 - surgery Humans Kidney Failure, Chronic - etiology Kidney Failure, Chronic - surgery Kidney Transplantation Liver, biliary tract, pancreas, portal circulation, spleen Medical sciences Pancreas Transplantation - methods Pancreas Transplantation - trends Patient Selection Perioperative Care Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases Surgery of the digestive system Tissue Donors |
title | Innovations in pancreas transplantation |
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