Glucose-inducible hypertrophy and suppression of anion efflux in rat beta cells

Hypertrophy of beta cells from obese fa/fa rats is associated with increased sensitivity to basal glucose. Exposure to glucose in culture distorts insulin secretion more in beta cells from large than small islets from fa/fa rats. The aim of the present study is to investigate whether increased beta...

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Veröffentlicht in:	Journal of endocrinology 2002-04, Vol.173 (1), p.45-52
Hauptverfasser:	Chan, CB, Saleh, MC, Purje, A, MacPhail, RM
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anions - metabolism Biological and medical sciences Cell Size - drug effects Cells, Cultured Dose-Response Relationship, Drug Female Glucose - pharmacology Hemolytic Plaque Technique Islets of Langerhans - metabolism Islets of Langerhans - pathology Male Models, Animal Obesity - metabolism Obesity - pathology Rats Rats, Zucker Time Factors
Online-Zugang:	Volltext
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