Injury to retinal ganglion cells induces expression of the small heat shock protein Hsp27 in the rat visual system

Optic nerve transection results in apoptotic cell death of most adult rat retinal ganglion cells that begins at 4 days and leaves few surviving neurons at 14 days post-injury [Berkelaar et al. (1994) J. Neurosci. 14, 4368–4374]. The small heat shock protein Hsp27 has recently been shown to play a ro...

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