Stereoselective binding of 2-(4-biphenylyl)-3-substituted-3-hydroxypropionic acids on an immobilised human serum albumin chiral stationary phase

A series of 2-(4-biphenylyl)-3,3'-hydroxy-substituted phenyl propionic acid, with anti-inflammatory properties, bearing two chiral centres, were studied by HPLC upon HSA-CSP (human serum albumin-based chiral stationary phase). The compounds were analysed in their stereoisomeric erythro and thre...

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Veröffentlicht in:	Journal of chromatography. B, Analytical technologies in the biomedical and life sciences Analytical technologies in the biomedical and life sciences, 2002-02, Vol.768 (1), p.137-145
Hauptverfasser:	Andrisano, V, Gotti, R, Recanatini, M, Cavalli, A, Varoli, L, Bertucci, C
Format:	Artikel
Sprache:	eng
Schlagworte:	Chromatography, High Pressure Liquid - instrumentation Circular Dichroism Lactic Acid - analogs & derivatives Lactic Acid - metabolism Protein Binding Quantitative Structure-Activity Relationship Serum Albumin - metabolism Stereoisomerism
Online-Zugang:	Volltext
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