Melanosomal Proteins - Role in Melanin Polymerization

Melanin, the major determinant of skin colour, is a tyrosine‐based heteropolymer of indeterminate molecular weight. In vivo, melanin synthesis occurs within highly specialized organelles called melanosomes. Coated vesicles encapsulating the enzyme tyrosinase and tyrosinase related proteins, fuse wit...

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Veröffentlicht in:	Pigment cell research 2002-04, Vol.15 (2), p.127-133
Hauptverfasser:	Sharma, Savitha, Wagh, Sushama, Govindarajan, Raman
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biopolymers Electrophoresis, Polyacrylamide Gel - methods Initiation of Polymerization Melanin-binding Melanins - chemistry Melanins - metabolism Melanoma Melanosomes - chemistry Melanosomes - metabolism Mice Molecular Biology - methods Preparative SDS-PAGE Proteins - isolation & purification Proteins - metabolism Solid-phase binding assay Tumor Cells, Cultured
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