Promoter methylation controls the expression of MAGE2, 3 and 4 genes in human cutaneous melanoma

Cancer-testis antigens expressed by different-histotype transformed cells are suitable targets for tumor immunotherapy. However, their heterogeneous expression in neoplastic lesions limits the eligibility of patients for cancer-testis antigen-directed vaccination, and low levels of cancer-testis ant...

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Veröffentlicht in:	Journal of immunotherapy (1997) 2002, Vol.25 (1), p.16-26
Hauptverfasser:	SIGALOTTI, Luca, CORAL, Sandra, NARDI, Gianpaolo, SPESSOTTO, Alberto, CORTINI, Enzo, CATTAROSSI, Ilaria, COLIZZI, Francesca, ALTOMONTE, Maresa, MAIO, Michele
Format:	Artikel
Sprache:	eng
Schlagworte:	Antigens, Neoplasm Antineoplastic agents Azacitidine - pharmacology Biological and medical sciences DNA Methylation General aspects Green Fluorescent Proteins Humans Luminescent Proteins - genetics Medical sciences Melanoma - genetics Melanoma - immunology Melanoma - secondary Membrane Proteins Neoplasm Proteins - genetics Pharmacology. Drug treatments Promoter Regions, Genetic Proteins Skin Neoplasms - genetics Skin Neoplasms - immunology Skin Neoplasms - secondary Tumor Cells, Cultured
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