Hyperthermia exhibits anti-vascular activity in the s.c. BT4An rat glioma: lack of interaction with the angiogenesis inhibitor batimastat

We investigated the anti-vascular activity of local hyperthermia (44 degrees C, 60 min) in s.c. BT4An rat gliomas, and the influence on tumour growth of hyperthermia and the anti-angiogenic compound batimastat (30 mg/kg i.p.). Heat-induced vascular damage was assessed in small (82 mm3) and large (17...

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Veröffentlicht in:	International journal of hyperthermia 2002-03, Vol.18 (2), p.141-152
Hauptverfasser:	EIKESDAL, H. P, BJORKHAUG, S. T, DAHL, O
Format:	Artikel
Sprache:	eng
Schlagworte:	Angiogenesis Inhibitors - therapeutic use Animals Antineoplastic agents Biological and medical sciences Brain Neoplasms - blood supply Brain Neoplasms - therapy Combined treatments (chemotherapy of immunotherapy associated with an other treatment) Female Glioma - blood supply Glioma - therapy Hyperthermia, Induced Male Medical sciences Pharmacology. Drug treatments Phenylalanine - analogs & derivatives Phenylalanine - therapeutic use Rats Thiophenes - therapeutic use
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