Comparison of in vitro activities of biotransformation enzymes in pig, cattle, goat and sheep

In vitro activities of cytochromes P450 (7-alkyl/aryloxyresorufin dealkyl(aryl)ases, testosterone hydroxylase/oxidase, 6-chlorzoxazone hydroxylase, 7-methoxy-4-trifluoromethyl-coumarin demethylase, and lauric acid hydroxylases), reductases of carbonyl group (toward metyrapone, daunorubicin, glyceral...

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Veröffentlicht in:	Research in veterinary science 2004-02, Vol.76 (1), p.43-51
Hauptverfasser:	Szotáková, B., Baliharová, V., Lamka, J., Nožinová, E., Wsól, V., Velı&#x0301, k, J., Machala, M., Neča, J., Souček, P., Šusová, S., Skálová, L.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biotransformation Cattle cytochrome P-450 Cytochrome P-450 CYP4A - pharmacokinetics Cytochrome P-450 Enzyme System - pharmacokinetics Cytochrome P450 Drug metabolism enzyme activity Enzymes Farm Animals Food-Producing animals genetic variation Goats GST immunocytochemistry Laboratory animals liver microsomes Male pharmacokinetics pharmacology Proteins Reductases of carbonyl group Sexual Maturation Sheep species differences Species Specificity Swine UGT Veterinary medicine xenobiotics
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