Genetic and cytological characterization of the RecA-homologous proteins Rad51 and Dmc1 of Schizosaccharomyces pombe

The Schizosaccharomyces pombe rad51(+) and dmc1(+) genes code for homologues of the Escherichia coli recombination protein RecA. Deletion of rad51(+) causes slow growth, retardation of cell division and a decrease in viability. rad51Delta cells have a defect in mating-type switching. The DNA modific...

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Veröffentlicht in:	Current genetics 2004, Vol.44 (6), p.317-328
Hauptverfasser:	Grishchuk, A.L, Kraehenbuehl, R, Molnar, M, Fleck, O, Kohli, J
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine Triphosphatases Animals Antibodies, Monoclonal Cell Compartmentation Cell Cycle Proteins - biosynthesis Cell Cycle Proteins - genetics Cell division Crossing Over, Genetic Dmc1 protein DNA-binding proteins DNA-Binding Proteins - biosynthesis DNA-Binding Proteins - genetics E coli Epitopes Escherichia coli Gene Deletion gene expression Gene Expression Regulation, Fungal genes Genetic Vectors Green Fluorescent Proteins homologous recombination Immunochemistry Luminescent Proteins - biosynthesis Luminescent Proteins - genetics meiosis Mice Mice, Knockout mutants Nuclear Proteins phenotype Phosphate-Binding Proteins protein-protein interactions Rad51 protein Rad51 Recombinase Rec A Recombinases - genetics Recombinant Fusion Proteins - biosynthesis Recombinant Fusion Proteins - genetics Schizosaccharomyces - genetics Schizosaccharomyces - metabolism Schizosaccharomyces - ultrastructure Schizosaccharomyces pombe Schizosaccharomyces pombe Proteins Sequence Homology, Nucleic Acid transcription (genetics) Yeast
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