[ 3H]Resiniferatoxin autoradiography in the CNS of wild-type and TRPV1 null mice defines TRPV1 (VR-1) protein distribution

Knowledge of the distribution and function of the vanilloid receptor (VR-1 or TRPV1) in the CNS lacks the detailed appreciation of its role in the peripheral nervous system. The radiolabelled vanilloid agonist [ 3H]resiniferatoxin (RTX) has been used to indicate the presence of TRPV1 receptor protei...

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Veröffentlicht in:	Brain research 2004-01, Vol.995 (2), p.176-183
Hauptverfasser:	Roberts, Jennifer C, Davis, John B, Benham, Christopher D
Format:	Artikel
Sprache:	eng
Schlagworte:	[ 3H]Resiniferatoxin autoradiography Animals Autoradiography Blotting, Southern Brain - metabolism Diterpenes - pharmacology Mice Receptors, Drug - metabolism Reverse Transcriptase Polymerase Chain Reaction RNA, Messenger - analysis Spinal Cord - metabolism TRP channel Vanilloid receptor
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