MEDULLOBLASTOMA IN CHILDREN 0-3 YEARS OLD: Forty Years' Experience in Slovenia
Twenty-one children 0-3 years with MB were admitted 1960-1996, of 14 before treated 1984, 3 had no treatment, 5 had postoperative RT, one had radioactive gold IT. Seven treated 1986-1996 had preradiation Cht, 5 with HDCy. Of the 14 treated before 1984, 12 died within 1 year, one after 42 years in hy...
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Veröffentlicht in: | Pediatric hematology and oncology 2004, Vol.21 (1), p.17-21 |
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creator | Kopa, Štefan Jereb, Berta |
description | Twenty-one children 0-3 years with MB were admitted 1960-1996, of 14 before treated 1984, 3 had no treatment, 5 had postoperative RT, one had radioactive gold IT. Seven treated 1986-1996 had preradiation Cht, 5 with HDCy. Of the 14 treated before 1984, 12 died within 1 year, one after 42 years in hypopharynx cancer, one is alive, of normal height and working. Of the 7 treated 1986-1996, 3 with disseminated disease died. Four are longtime survivors, 2 treated with reduced doses of RT of normal development. Preradiation Cht with HDCy and reduced doses of RT seems to be a reasonable approach. |
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Seven treated 1986-1996 had preradiation Cht, 5 with HDCy. Of the 14 treated before 1984, 12 died within 1 year, one after 42 years in hypopharynx cancer, one is alive, of normal height and working. Of the 7 treated 1986-1996, 3 with disseminated disease died. Four are longtime survivors, 2 treated with reduced doses of RT of normal development. Preradiation Cht with HDCy and reduced doses of RT seems to be a reasonable approach.</description><subject>Antineoplastic Combined Chemotherapy Protocols - therapeutic use</subject><subject>Chemotherapy, Adjuvant</subject><subject>Child, Preschool</subject><subject>children</subject><subject>Combined Modality Therapy</subject><subject>Female</subject><subject>Follow-Up Studies</subject><subject>Humans</subject><subject>Infant</subject><subject>Infant, Newborn</subject><subject>Male</subject><subject>medulloblastoma</subject><subject>Medulloblastoma - drug therapy</subject><subject>Medulloblastoma - mortality</subject><subject>Medulloblastoma - radiotherapy</subject><subject>Medulloblastoma - therapy</subject><subject>preradiation chemotherapy</subject><subject>Slovenia</subject><subject>Survival Rate</subject><issn>0888-0018</issn><issn>1521-0669</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2004</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kE1PGzEURa2qCFLgB7BBXrWrgeePsZ22mzQZINKQSAQWrCyPY4tBk3FqT9rm3zMokSqExOot7rlXTwehMwIXBBRcglIKgAAfAhWMcf4JDUhOSQZCDD-jwWue9YA6Ql9SegYAyiQ9REeECwEM6ADNbovJQ1nOf5Wjxf38doSnMzy-mZaTu2KGIWP4sRjdLfC8nHzHVyF2W_zoTEzfcPFv7WLtWutw3eJFE_64tjYn6MCbJrnT_T1GD1fF_fgmK-fX0_GozCwH2mVUMZnnQ-KpI9JSCc7KShqViyVwImFIqOKeCi88ZaxynjmbV5URovIyN5wdo6-73XUMvzcudXpVJ-uaxrQubJKWJBdcKdmDZAfaGFKKzut1rFcmbjUB_SpRv5PYd87345tq5Zb_G3trPfBzB9StD3Fl_obYLHVntk2IPprW1kmzj_Z_vKk_OdN0T9ZEp5_DJra9uA--ewGRFIv9</recordid><startdate>2004</startdate><enddate>2004</enddate><creator>Kopa, Štefan</creator><creator>Jereb, Berta</creator><general>Informa UK Ltd</general><general>Taylor & Francis</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>2004</creationdate><title>MEDULLOBLASTOMA IN CHILDREN 0-3 YEARS OLD: Forty Years' Experience in Slovenia</title><author>Kopa, Štefan ; Jereb, Berta</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c402t-28375591f2e17c270ec7b7a856d0417091284f26f6f233bef3ec5bba66bf75a43</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2004</creationdate><topic>Antineoplastic Combined Chemotherapy Protocols - therapeutic use</topic><topic>Chemotherapy, Adjuvant</topic><topic>Child, Preschool</topic><topic>children</topic><topic>Combined Modality Therapy</topic><topic>Female</topic><topic>Follow-Up Studies</topic><topic>Humans</topic><topic>Infant</topic><topic>Infant, Newborn</topic><topic>Male</topic><topic>medulloblastoma</topic><topic>Medulloblastoma - drug therapy</topic><topic>Medulloblastoma - mortality</topic><topic>Medulloblastoma - radiotherapy</topic><topic>Medulloblastoma - therapy</topic><topic>preradiation chemotherapy</topic><topic>Slovenia</topic><topic>Survival Rate</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Kopa, Štefan</creatorcontrib><creatorcontrib>Jereb, Berta</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Pediatric hematology and oncology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kopa, Štefan</au><au>Jereb, Berta</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>MEDULLOBLASTOMA IN CHILDREN 0-3 YEARS OLD: Forty Years' Experience in Slovenia</atitle><jtitle>Pediatric hematology and oncology</jtitle><addtitle>Pediatr Hematol Oncol</addtitle><date>2004</date><risdate>2004</risdate><volume>21</volume><issue>1</issue><spage>17</spage><epage>21</epage><pages>17-21</pages><issn>0888-0018</issn><eissn>1521-0669</eissn><abstract>Twenty-one children 0-3 years with MB were admitted 1960-1996, of 14 before treated 1984, 3 had no treatment, 5 had postoperative RT, one had radioactive gold IT. Seven treated 1986-1996 had preradiation Cht, 5 with HDCy. Of the 14 treated before 1984, 12 died within 1 year, one after 42 years in hypopharynx cancer, one is alive, of normal height and working. Of the 7 treated 1986-1996, 3 with disseminated disease died. Four are longtime survivors, 2 treated with reduced doses of RT of normal development. Preradiation Cht with HDCy and reduced doses of RT seems to be a reasonable approach.</abstract><cop>England</cop><pub>Informa UK Ltd</pub><pmid>14660302</pmid><doi>10.1080/08880010490263344</doi><tpages>5</tpages></addata></record> |
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subjects | Antineoplastic Combined Chemotherapy Protocols - therapeutic use Chemotherapy, Adjuvant Child, Preschool children Combined Modality Therapy Female Follow-Up Studies Humans Infant Infant, Newborn Male medulloblastoma Medulloblastoma - drug therapy Medulloblastoma - mortality Medulloblastoma - radiotherapy Medulloblastoma - therapy preradiation chemotherapy Slovenia Survival Rate |
title | MEDULLOBLASTOMA IN CHILDREN 0-3 YEARS OLD: Forty Years' Experience in Slovenia |
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