MEDULLOBLASTOMA IN CHILDREN 0-3 YEARS OLD: Forty Years' Experience in Slovenia

Twenty-one children 0-3 years with MB were admitted 1960-1996, of 14 before treated 1984, 3 had no treatment, 5 had postoperative RT, one had radioactive gold IT. Seven treated 1986-1996 had preradiation Cht, 5 with HDCy. Of the 14 treated before 1984, 12 died within 1 year, one after 42 years in hy...

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Veröffentlicht in:Pediatric hematology and oncology 2004, Vol.21 (1), p.17-21
Hauptverfasser: Kopa, Štefan, Jereb, Berta
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description Twenty-one children 0-3 years with MB were admitted 1960-1996, of 14 before treated 1984, 3 had no treatment, 5 had postoperative RT, one had radioactive gold IT. Seven treated 1986-1996 had preradiation Cht, 5 with HDCy. Of the 14 treated before 1984, 12 died within 1 year, one after 42 years in hypopharynx cancer, one is alive, of normal height and working. Of the 7 treated 1986-1996, 3 with disseminated disease died. Four are longtime survivors, 2 treated with reduced doses of RT of normal development. Preradiation Cht with HDCy and reduced doses of RT seems to be a reasonable approach.
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source MEDLINE; Taylor & Francis:Master (3349 titles); Taylor & Francis Medical Library - CRKN
subjects Antineoplastic Combined Chemotherapy Protocols - therapeutic use
Chemotherapy, Adjuvant
Child, Preschool
children
Combined Modality Therapy
Female
Follow-Up Studies
Humans
Infant
Infant, Newborn
Male
medulloblastoma
Medulloblastoma - drug therapy
Medulloblastoma - mortality
Medulloblastoma - radiotherapy
Medulloblastoma - therapy
preradiation chemotherapy
Slovenia
Survival Rate
title MEDULLOBLASTOMA IN CHILDREN 0-3 YEARS OLD: Forty Years' Experience in Slovenia
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