Antimicrobial Resistance Trends and Outbreak Frequency in United States Hospitals
We assessed resistance rates and trends for important antimicrobial-resistant pathogens (oxacillin-resistant Staphylococcus aureus [ORSA], vancomycin-resistant Enterococcus species [VRE], ceftazidime-resistant Klebsiella species [K-ESBL], and ciprofloxacin-resistant Escherichia coli [QREC]), the fre...
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| Veröffentlicht in: | Clinical infectious diseases 2004-01, Vol.38 (1), p.78-85 |
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| creator | Diekema, Daniel J. BootsMiller, Bonnie J. Vaughn, Thomas E. Woolson, Robert F. Yankey, Jon W. Ernst, Erika J. Flach, Stephen D. Ward, Marcia M. Franciscus, Carrie L. J. Pfaller, Michael A. Doebbeling, Bradley N. |
| description | We assessed resistance rates and trends for important antimicrobial-resistant pathogens (oxacillin-resistant Staphylococcus aureus [ORSA], vancomycin-resistant Enterococcus species [VRE], ceftazidime-resistant Klebsiella species [K-ESBL], and ciprofloxacin-resistant Escherichia coli [QREC]), the frequency of outbreaks of infection with these resistant pathogens, and the measures taken to control resistance in a stratified national sample of 670 hospitals. Four hundred ninety-four (74%) of 670 surveys were returned. Resistance rates were highest for ORSA (36%), followed by VRE (10%), QREC (6%), and K-ESBL (5%). Two-thirds of hospitals reported increasing ORSA rates, whereas only 4% reported decreasing rates, and 24% reported ORSA outbreaks within the previous year. Most hospitals (87%) reported having implemented measures to rapidly detect resistance, but only ∼50% reported having provided appropriate resources for antimicrobial resistance prevention (53%) or having implemented antimicrobial use guidelines (60%). The most common resistant pathogen in US hospitals is ORSA, which accounts for many recognized outbreaks and is increasing in frequency in most facilities. Current practices to prevent and control antimicrobial resistance are inadequate. |
| doi_str_mv | 10.1086/380457 |
| format | Article |
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J. ; Pfaller, Michael A. ; Doebbeling, Bradley N.</creator><creatorcontrib>Diekema, Daniel J. ; BootsMiller, Bonnie J. ; Vaughn, Thomas E. ; Woolson, Robert F. ; Yankey, Jon W. ; Ernst, Erika J. ; Flach, Stephen D. ; Ward, Marcia M. ; Franciscus, Carrie L. J. ; Pfaller, Michael A. ; Doebbeling, Bradley N.</creatorcontrib><description>We assessed resistance rates and trends for important antimicrobial-resistant pathogens (oxacillin-resistant Staphylococcus aureus [ORSA], vancomycin-resistant Enterococcus species [VRE], ceftazidime-resistant Klebsiella species [K-ESBL], and ciprofloxacin-resistant Escherichia coli [QREC]), the frequency of outbreaks of infection with these resistant pathogens, and the measures taken to control resistance in a stratified national sample of 670 hospitals. Four hundred ninety-four (74%) of 670 surveys were returned. Resistance rates were highest for ORSA (36%), followed by VRE (10%), QREC (6%), and K-ESBL (5%). Two-thirds of hospitals reported increasing ORSA rates, whereas only 4% reported decreasing rates, and 24% reported ORSA outbreaks within the previous year. Most hospitals (87%) reported having implemented measures to rapidly detect resistance, but only ∼50% reported having provided appropriate resources for antimicrobial resistance prevention (53%) or having implemented antimicrobial use guidelines (60%). The most common resistant pathogen in US hospitals is ORSA, which accounts for many recognized outbreaks and is increasing in frequency in most facilities. Current practices to prevent and control antimicrobial resistance are inadequate.</description><identifier>ISSN: 1058-4838</identifier><identifier>EISSN: 1537-6591</identifier><identifier>DOI: 10.1086/380457</identifier><identifier>PMID: 14679451</identifier><identifier>CODEN: CIDIEL</identifier><language>eng</language><publisher>Chicago, IL: The University of Chicago Press</publisher><subject>Anti-Bacterial Agents - pharmacology ; Antibacterial agents ; Antibiotic resistance ; Antibiotics. Antiinfectious agents. Antiparasitic agents ; Antimicrobials ; Bacteria - drug effects ; Bacteria - isolation & purification ; Bacterial diseases ; Bacterial Infections - epidemiology ; Bacterial Infections - microbiology ; Biological and medical sciences ; Cross Infection - epidemiology ; Cross Infection - microbiology ; Data Collection ; Disease Outbreaks ; Drug Resistance, Bacterial - physiology ; Enterococcus ; Epidemiology ; Escherichia coli ; Geographic regions ; Hospital beds ; Hospitals ; Human bacterial diseases ; Humans ; Infections ; Infectious diseases ; Klebsiella ; Major Articles ; Medical sciences ; Microbial Sensitivity Tests ; Pathogens ; Pharmacology. 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J.</creatorcontrib><creatorcontrib>Pfaller, Michael A.</creatorcontrib><creatorcontrib>Doebbeling, Bradley N.</creatorcontrib><title>Antimicrobial Resistance Trends and Outbreak Frequency in United States Hospitals</title><title>Clinical infectious diseases</title><addtitle>Clinical Infectious Diseases</addtitle><addtitle>Clinical Infectious Diseases</addtitle><description>We assessed resistance rates and trends for important antimicrobial-resistant pathogens (oxacillin-resistant Staphylococcus aureus [ORSA], vancomycin-resistant Enterococcus species [VRE], ceftazidime-resistant Klebsiella species [K-ESBL], and ciprofloxacin-resistant Escherichia coli [QREC]), the frequency of outbreaks of infection with these resistant pathogens, and the measures taken to control resistance in a stratified national sample of 670 hospitals. Four hundred ninety-four (74%) of 670 surveys were returned. Resistance rates were highest for ORSA (36%), followed by VRE (10%), QREC (6%), and K-ESBL (5%). Two-thirds of hospitals reported increasing ORSA rates, whereas only 4% reported decreasing rates, and 24% reported ORSA outbreaks within the previous year. Most hospitals (87%) reported having implemented measures to rapidly detect resistance, but only ∼50% reported having provided appropriate resources for antimicrobial resistance prevention (53%) or having implemented antimicrobial use guidelines (60%). The most common resistant pathogen in US hospitals is ORSA, which accounts for many recognized outbreaks and is increasing in frequency in most facilities. Current practices to prevent and control antimicrobial resistance are inadequate.</description><subject>Anti-Bacterial Agents - pharmacology</subject><subject>Antibacterial agents</subject><subject>Antibiotic resistance</subject><subject>Antibiotics. Antiinfectious agents. Antiparasitic agents</subject><subject>Antimicrobials</subject><subject>Bacteria - drug effects</subject><subject>Bacteria - isolation & purification</subject><subject>Bacterial diseases</subject><subject>Bacterial Infections - epidemiology</subject><subject>Bacterial Infections - microbiology</subject><subject>Biological and medical sciences</subject><subject>Cross Infection - epidemiology</subject><subject>Cross Infection - microbiology</subject><subject>Data Collection</subject><subject>Disease Outbreaks</subject><subject>Drug Resistance, Bacterial - physiology</subject><subject>Enterococcus</subject><subject>Epidemiology</subject><subject>Escherichia coli</subject><subject>Geographic regions</subject><subject>Hospital beds</subject><subject>Hospitals</subject><subject>Human bacterial diseases</subject><subject>Humans</subject><subject>Infections</subject><subject>Infectious diseases</subject><subject>Klebsiella</subject><subject>Major Articles</subject><subject>Medical sciences</subject><subject>Microbial Sensitivity Tests</subject><subject>Pathogens</subject><subject>Pharmacology. 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J.</au><au>Pfaller, Michael A.</au><au>Doebbeling, Bradley N.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Antimicrobial Resistance Trends and Outbreak Frequency in United States Hospitals</atitle><jtitle>Clinical infectious diseases</jtitle><stitle>Clinical Infectious Diseases</stitle><addtitle>Clinical Infectious Diseases</addtitle><date>2004-01-01</date><risdate>2004</risdate><volume>38</volume><issue>1</issue><spage>78</spage><epage>85</epage><pages>78-85</pages><issn>1058-4838</issn><eissn>1537-6591</eissn><coden>CIDIEL</coden><abstract>We assessed resistance rates and trends for important antimicrobial-resistant pathogens (oxacillin-resistant Staphylococcus aureus [ORSA], vancomycin-resistant Enterococcus species [VRE], ceftazidime-resistant Klebsiella species [K-ESBL], and ciprofloxacin-resistant Escherichia coli [QREC]), the frequency of outbreaks of infection with these resistant pathogens, and the measures taken to control resistance in a stratified national sample of 670 hospitals. Four hundred ninety-four (74%) of 670 surveys were returned. Resistance rates were highest for ORSA (36%), followed by VRE (10%), QREC (6%), and K-ESBL (5%). Two-thirds of hospitals reported increasing ORSA rates, whereas only 4% reported decreasing rates, and 24% reported ORSA outbreaks within the previous year. Most hospitals (87%) reported having implemented measures to rapidly detect resistance, but only ∼50% reported having provided appropriate resources for antimicrobial resistance prevention (53%) or having implemented antimicrobial use guidelines (60%). The most common resistant pathogen in US hospitals is ORSA, which accounts for many recognized outbreaks and is increasing in frequency in most facilities. Current practices to prevent and control antimicrobial resistance are inadequate.</abstract><cop>Chicago, IL</cop><pub>The University of Chicago Press</pub><pmid>14679451</pmid><doi>10.1086/380457</doi><tpages>8</tpages><oa>free_for_read</oa></addata></record> |
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| source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; JSTOR Archive Collection A-Z Listing; Oxford University Press Journals All Titles (1996-Current) |
| subjects | Anti-Bacterial Agents - pharmacology Antibacterial agents Antibiotic resistance Antibiotics. Antiinfectious agents. Antiparasitic agents Antimicrobials Bacteria - drug effects Bacteria - isolation & purification Bacterial diseases Bacterial Infections - epidemiology Bacterial Infections - microbiology Biological and medical sciences Cross Infection - epidemiology Cross Infection - microbiology Data Collection Disease Outbreaks Drug Resistance, Bacterial - physiology Enterococcus Epidemiology Escherichia coli Geographic regions Hospital beds Hospitals Human bacterial diseases Humans Infections Infectious diseases Klebsiella Major Articles Medical sciences Microbial Sensitivity Tests Pathogens Pharmacology. Drug treatments Staphylococcal infections, streptococcal infections, pneumococcal infections Staphylococcus aureus Surveillance Teaching hospitals United States - epidemiology |
| title | Antimicrobial Resistance Trends and Outbreak Frequency in United States Hospitals |
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