Post-transcriptional regulation of inducible nitric oxide synthase in chronic lymphocytic leukemia B cells in pro- and antiapoptotic culture conditions

Functional inducible NOS (iNOS) may be involved in the prolonged lifespan of chronic lymphocytic leukemia cells (B-CLL), although the exact mechanisms implicated remain elusive as yet. In this work, we have examined iNOS expression in normal B lymphocytes and B-CLL cells in pro- and antiapoptotic co...

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Veröffentlicht in:	Leukemia 2004-01, Vol.18 (1), p.48-56
Hauptverfasser:	TISCORNIA, A. C, CAYOTA, A, LANDONI, A. I, BRITO, C, OPPEZZO, P, VUILLIER, F, ROBELLO, C, DIGHIERO, G, GABUS, R, PRITSCH, O
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Aged, 80 and over Alternative Splicing Antineoplastic Agents - pharmacology Apoptosis - physiology B-Lymphocytes - enzymology Base Sequence Biological and medical sciences Caspase 3 Caspases - metabolism DNA (Cytosine-5-)-Methyltransferases - antagonists & inhibitors Female Gene Expression Regulation, Enzymologic Gene Expression Regulation, Leukemic Hematologic and hematopoietic diseases Humans Interleukin-4 - pharmacology Isoenzymes Leukemia, Lymphocytic, Chronic, B-Cell - enzymology Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis Male Medical sciences Middle Aged Molecular Sequence Data Nitric Oxide - physiology Nitric Oxide Synthase - genetics Nitric Oxide Synthase Type II RNA Processing, Post-Transcriptional RNA, Messenger - metabolism Sequence Deletion Sequence Homology, Nucleic Acid Signal Transduction Transcription, Genetic Vidarabine - analogs & derivatives Vidarabine - pharmacology
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