Expression profiling in transformed human B cells: influence of Btk mutations and comparison to B cell lymphomas using filter and oligonucleotide arrays

We have used both Clontech AtlasTM Human Hematology/Immunology cDNA microarrays, containing 588 genes, and Affymetrix oligonucleotide U95Av2 human array complementary to more than 12,500 genes to get a global view of genes expressed in Epstein‐Barr virus (EBV)‐transformed B cells and genes regulated...

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Veröffentlicht in:	European journal of immunology 2002-04, Vol.32 (4), p.982-993
Hauptverfasser:	Islam, Tahmina C., Lindvall, Jessica, Wennborg, Anders, Brandén, Lars J., Rabbani, Hodjatallah, Smith, C. I. Edvard
Format:	Artikel
Sprache:	eng
Schlagworte:	Agammaglobulinemia - enzymology Agammaglobulinemia - genetics Btk Btk protein Cell Line, Transformed - metabolism Cell Transformation, Viral Computer Systems DNA microarrays DNA, Complementary - genetics Epstein Barr virus Gene Expression Profiling Gene Expression Regulation, Viral Herpesvirus 4, Human - physiology Humans Lymphoma Microarray Oligonucleotide Array Sequence Analysis oligonucleotides Polymerase Chain Reaction Protein-Tyrosine Kinases - deficiency Protein-Tyrosine Kinases - genetics Protein-Tyrosine Kinases - physiology Subtraction Technique X Chromosome - genetics X‐linked agammaglobulinemia
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