NF-kappaB/Rel-mediated regulation of apoptosis in hematologic malignancies and normal hematopoietic progenitors

The activity of NF-kappaB/Rel transcription factors can downmodulate apoptosis in normal and neoplastic cells of the hematologic and other compartments, contributing in maintaining neoplastic clone survival and impairing response to therapy. Alterations in nfkappab or ikappaB genes are documented in...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Leukemia 2004-01, Vol.18 (1), p.11-17
Hauptverfasser:	Turco, M C, Romano, M F, Petrella, A, Bisogni, R, Tassone, P, Venuta, S
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Apoptosis Hematologic Neoplasms - pathology Hematopoietic Stem Cells - pathology Humans NF-kappa B - physiology Proto-Oncogene Proteins c-rel - physiology Signal Transduction - drug effects
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!