Regulation of Sertoli Cell Number and Activity by Follicle-Stimulating Hormone and Androgen during Postnatal Development in the Mouse

The roles of FSH and androgen in the postnatal development of Sertoli cell number and function have been investigated using mice that lack FSH (FSHβKO), FSH-receptors (FSHRKO), or androgen receptors (Tfm). At birth and d 5, Sertoli cell number was normal in FSHRKO and FSHβKO mice, but was significan...

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Veröffentlicht in:	Endocrinology (Philadelphia) 2004-01, Vol.145 (1), p.318-329
Hauptverfasser:	Johnston, Heather, Baker, Paul J, Abel, Margaret, Charlton, Harry M, Jackson, Gary, Fleming, Lynne, Kumar, T. Rajendra, O’Shaughnessy, Peter J
Format:	Artikel
Sprache:	eng
Schlagworte:	Androgen receptors Androgens Androgens - metabolism Animals Biological and medical sciences Birth Cell growth Cell number Cell proliferation Cryptorchidism Female Fetuses Follicle Stimulating Hormone, beta Subunit - genetics Follicle Stimulating Hormone, beta Subunit - metabolism Follicle-stimulating hormone Fundamental and applied biological sciences. Psychology Gene expression Gene Expression Regulation, Developmental Male Mice Mice, Inbred C57BL Mice, Mutant Strains Neonates Postpartum period Receptor mechanisms Receptors Receptors, Androgen - genetics Receptors, FSH - genetics RNA, Messenger - analysis Sertoli Cells - cytology Sertoli Cells - metabolism Testis - cytology Testis - growth & development Testis - metabolism Testosterone Vertebrates: endocrinology
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