Antioxidant Activity of Nebivolol in the Rat Aorta

The β-blocker nebivolol is a racemic mixture of d- and l- enantiomers that displays negative inotropic as well as direct vasorelaxant activity. In addition, it has been proposed that nebivolol exerts endothelium-protective effects caused by its antioxidant properties. In the present study we investi...

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Veröffentlicht in:	Journal of cardiovascular pharmacology 2004-01, Vol.43 (1), p.148-153
Hauptverfasser:	de Groot, Annemieke A, Mathy, Marie-Jeanne, van Zwieten, Pieter A, Peters, Stephan L. M
Format:	Artikel
Sprache:	eng
Schlagworte:	Adrenergic beta-Antagonists - pharmacology Animals Aorta Benzopyrans - pharmacology Chromatography, High Pressure Liquid Ethanolamines - pharmacology Male Muscle, Smooth, Vascular - drug effects Nebivolol Oxidative Stress - drug effects Rats Rats, Inbred WKY Reactive Oxygen Species
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