Budesonide versus mesalamine for maintaining remission in patients refusing other immunomodulators for steroid-dependent Crohn's disease

Background & Aims: To compare the efficacy of controlled-release budesonide capsules with that of mesalamine for maintaining remission and improving quality of life (QOL) in patients with steroid-dependent Crohn's disease. Methods: Fifty-seven patients (25 men; mean age, 32 ± 10.1 yr) with...

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Veröffentlicht in:	Clinical gastroenterology and hepatology 2003-03, Vol.1 (2), p.122-128
Hauptverfasser:	Mantzaris, Gerassimos J., Petraki, Kalliopi, Sfakianakis, Michael, Archavlis, Emmanuel, Christidou, Angeliki, Chadio-Iordanides, Helen, Triadaphyllou, George
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Anti-Inflammatory Agents - therapeutic use Anti-Inflammatory Agents, Non-Steroidal - therapeutic use Budesonide - therapeutic use Crohn Disease - drug therapy Female Humans Male Mesalamine - therapeutic use Middle Aged Prospective Studies Quality of Life Remission Induction Single-Blind Method Treatment Outcome
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Zusammenfassung:	Background & Aims: To compare the efficacy of controlled-release budesonide capsules with that of mesalamine for maintaining remission and improving quality of life (QOL) in patients with steroid-dependent Crohn's disease. Methods: Fifty-seven patients (25 men; mean age, 32 ± 10.1 yr) with quiescent steroid-dependent Crohn's ileitis, ileocolitis, or colitis (Crohn's disease activity index
ISSN:	1542-3565 1542-7714
DOI:	10.1053/cgh.2003.50015