Unusual codon 69 insertions: influence on human immunodeficiency virus type 1 reverse transcriptase drug susceptibility

Introduction: Multiple amino acid changes in the reverse transcriptase (RT) enzyme of the human immunodeficiency virus 1 (HIV-1) confer simultaneous resistance to most nucleoside RT inhibitors (NRTI). It may take place through different pathways: one of these is the codon 69 insertion, which can inv...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of clinical virology 2004, Vol.29 (1), p.27-32
Hauptverfasser:	Bulgheroni, Elisabetta, Croce, Francesco, Citterio, Paola, Viganò, Ottavia, Visonà, Raffaella, Sala, Eugenio, Galli, Massimo, Rusconi, Stefano
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Substitution Anti-HIV Agents - pharmacology Anti-HIV Agents - therapeutic use Biological and medical sciences Codon Codon 69 Drug resistance Drug Resistance, Multiple, Viral Drug Therapy, Combination Fundamental and applied biological sciences. Psychology HIV Infections - drug therapy HIV Infections - virology HIV Reverse Transcriptase - drug effects HIV Reverse Transcriptase - genetics HIV-1 - drug effects HIV-1 - enzymology Human immunodeficiency virus 1 Human immunodeficiency virus 1 (HIV-1) Human viral diseases Humans Infectious diseases Medical sciences Microbial Sensitivity Tests Microbiology Miscellaneous Molecular Sequence Data Reverse transcriptase Reverse Transcriptase Inhibitors - pharmacology Reverse Transcriptase Inhibitors - therapeutic use Sequence Analysis, DNA Viral diseases Viral diseases of the lymphoid tissue and the blood. Aids Virology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!