Mycobacterial peritonitis in pediatric peritoneal dialysis patients

Peritonitis is the most common complication and the leading cause of death in pediatric peritoneal dialysis (PD) patients. According to the most recent data available from the North American Pediatric Renal Transplant Cooperative Study (NAPRTCS), approximately 25% of pediatric PD patients who die su...

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Veröffentlicht in:Pediatric nephrology (Berlin, West) West), 2004-01, Vol.19 (1), p.114-117
Hauptverfasser: Ferrara, Elizabeth, Lemire, Jacques, Grimm, Paul C, Reznik, Vivian M, Mendoza, Stanley A, Leake, John A, Benador, Nadine M
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container_end_page 117
container_issue 1
container_start_page 114
container_title Pediatric nephrology (Berlin, West)
container_volume 19
creator Ferrara, Elizabeth
Lemire, Jacques
Grimm, Paul C
Reznik, Vivian M
Mendoza, Stanley A
Leake, John A
Benador, Nadine M
description Peritonitis is the most common complication and the leading cause of death in pediatric peritoneal dialysis (PD) patients. According to the most recent data available from the North American Pediatric Renal Transplant Cooperative Study (NAPRTCS), approximately 25% of pediatric PD patients who die succumb to infection. There are no reported cases of Mycobacterium tuberculosis (MTB) or Mycobacterium avium-intracellulare peritonitis in the NAPRTCS registry. With an increasing incidence of MTB worldwide and the impairment of cellular immunity in chronic renal failure patients, it is not surprising that mycobacterium peritonitis can occur in PD patients. We report two pediatric PD patients with mycobacterial peritoneal infection diagnosed over an 11-year period at our institution. One patient presented with a malfunctioning Tenckhoff catheter and again 3 years later with hyponatremia and ascites. The other presented with recurrent culture-negative peritonitis. These cases illustrate the importance of more extensive evaluation of PD complications, to include evaluation for mycobacterium with special media or peritoneal biopsy, in the above clinical settings if the routine work-up is unrevealing.
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subjects Adolescent
Case studies
Causes of
Child
Continuous ambulatory peritoneal dialysis
Female
Humans
Mycobacterium avium complex
Mycobacterium avium Complex - isolation & purification
Mycobacterium Infections - diagnosis
Mycobacterium Infections - microbiology
Mycobacterium tuberculosis
Mycobacterium tuberculosis - isolation & purification
Peritoneal dialysis
Peritoneal Dialysis - adverse effects
Peritonitis
Peritonitis - microbiology
Risk factors
title Mycobacterial peritonitis in pediatric peritoneal dialysis patients
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