Mycobacterial peritonitis in pediatric peritoneal dialysis patients
Peritonitis is the most common complication and the leading cause of death in pediatric peritoneal dialysis (PD) patients. According to the most recent data available from the North American Pediatric Renal Transplant Cooperative Study (NAPRTCS), approximately 25% of pediatric PD patients who die su...
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Veröffentlicht in: | Pediatric nephrology (Berlin, West) West), 2004-01, Vol.19 (1), p.114-117 |
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creator | Ferrara, Elizabeth Lemire, Jacques Grimm, Paul C Reznik, Vivian M Mendoza, Stanley A Leake, John A Benador, Nadine M |
description | Peritonitis is the most common complication and the leading cause of death in pediatric peritoneal dialysis (PD) patients. According to the most recent data available from the North American Pediatric Renal Transplant Cooperative Study (NAPRTCS), approximately 25% of pediatric PD patients who die succumb to infection. There are no reported cases of Mycobacterium tuberculosis (MTB) or Mycobacterium avium-intracellulare peritonitis in the NAPRTCS registry. With an increasing incidence of MTB worldwide and the impairment of cellular immunity in chronic renal failure patients, it is not surprising that mycobacterium peritonitis can occur in PD patients. We report two pediatric PD patients with mycobacterial peritoneal infection diagnosed over an 11-year period at our institution. One patient presented with a malfunctioning Tenckhoff catheter and again 3 years later with hyponatremia and ascites. The other presented with recurrent culture-negative peritonitis. These cases illustrate the importance of more extensive evaluation of PD complications, to include evaluation for mycobacterium with special media or peritoneal biopsy, in the above clinical settings if the routine work-up is unrevealing. |
doi_str_mv | 10.1007/s00467-003-1348-1 |
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According to the most recent data available from the North American Pediatric Renal Transplant Cooperative Study (NAPRTCS), approximately 25% of pediatric PD patients who die succumb to infection. There are no reported cases of Mycobacterium tuberculosis (MTB) or Mycobacterium avium-intracellulare peritonitis in the NAPRTCS registry. With an increasing incidence of MTB worldwide and the impairment of cellular immunity in chronic renal failure patients, it is not surprising that mycobacterium peritonitis can occur in PD patients. We report two pediatric PD patients with mycobacterial peritoneal infection diagnosed over an 11-year period at our institution. One patient presented with a malfunctioning Tenckhoff catheter and again 3 years later with hyponatremia and ascites. The other presented with recurrent culture-negative peritonitis. These cases illustrate the importance of more extensive evaluation of PD complications, to include evaluation for mycobacterium with special media or peritoneal biopsy, in the above clinical settings if the routine work-up is unrevealing.</description><identifier>ISSN: 0931-041X</identifier><identifier>EISSN: 1432-198X</identifier><identifier>DOI: 10.1007/s00467-003-1348-1</identifier><identifier>PMID: 14648331</identifier><language>eng</language><publisher>Germany: Springer</publisher><subject>Adolescent ; Case studies ; Causes of ; Child ; Continuous ambulatory peritoneal dialysis ; Female ; Humans ; Mycobacterium avium complex ; Mycobacterium avium Complex - isolation & purification ; Mycobacterium Infections - diagnosis ; Mycobacterium Infections - microbiology ; Mycobacterium tuberculosis ; Mycobacterium tuberculosis - isolation & purification ; Peritoneal dialysis ; Peritoneal Dialysis - adverse effects ; Peritonitis ; Peritonitis - microbiology ; Risk factors</subject><ispartof>Pediatric nephrology (Berlin, West), 2004-01, Vol.19 (1), p.114-117</ispartof><rights>COPYRIGHT 2004 Springer</rights><rights>IPNA 2003</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c355t-cc99b2848e065ad999848765998897ee4bdb5deb9534a188402dbe93f0a3af4a3</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/14648331$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Ferrara, Elizabeth</creatorcontrib><creatorcontrib>Lemire, Jacques</creatorcontrib><creatorcontrib>Grimm, Paul C</creatorcontrib><creatorcontrib>Reznik, Vivian M</creatorcontrib><creatorcontrib>Mendoza, Stanley A</creatorcontrib><creatorcontrib>Leake, John A</creatorcontrib><creatorcontrib>Benador, Nadine M</creatorcontrib><title>Mycobacterial peritonitis in pediatric peritoneal dialysis patients</title><title>Pediatric nephrology (Berlin, West)</title><addtitle>Pediatr Nephrol</addtitle><description>Peritonitis is the most common complication and the leading cause of death in pediatric peritoneal dialysis (PD) patients. According to the most recent data available from the North American Pediatric Renal Transplant Cooperative Study (NAPRTCS), approximately 25% of pediatric PD patients who die succumb to infection. There are no reported cases of Mycobacterium tuberculosis (MTB) or Mycobacterium avium-intracellulare peritonitis in the NAPRTCS registry. With an increasing incidence of MTB worldwide and the impairment of cellular immunity in chronic renal failure patients, it is not surprising that mycobacterium peritonitis can occur in PD patients. We report two pediatric PD patients with mycobacterial peritoneal infection diagnosed over an 11-year period at our institution. One patient presented with a malfunctioning Tenckhoff catheter and again 3 years later with hyponatremia and ascites. The other presented with recurrent culture-negative peritonitis. These cases illustrate the importance of more extensive evaluation of PD complications, to include evaluation for mycobacterium with special media or peritoneal biopsy, in the above clinical settings if the routine work-up is unrevealing.</description><subject>Adolescent</subject><subject>Case studies</subject><subject>Causes of</subject><subject>Child</subject><subject>Continuous ambulatory peritoneal dialysis</subject><subject>Female</subject><subject>Humans</subject><subject>Mycobacterium avium complex</subject><subject>Mycobacterium avium Complex - isolation & purification</subject><subject>Mycobacterium Infections - diagnosis</subject><subject>Mycobacterium Infections - microbiology</subject><subject>Mycobacterium tuberculosis</subject><subject>Mycobacterium tuberculosis - isolation & purification</subject><subject>Peritoneal dialysis</subject><subject>Peritoneal Dialysis - adverse effects</subject><subject>Peritonitis</subject><subject>Peritonitis - microbiology</subject><subject>Risk factors</subject><issn>0931-041X</issn><issn>1432-198X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2004</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>BENPR</sourceid><recordid>eNpdkU1PwzAMhiMEYmPwA7igiQO3gN0kTXJEE1_SEBeQdovSNmWZunY06WH_nkwbmkQubxw_thy_hFwj3COAfAgAPJcUgFFkXFE8IWPkLKOo1eKUjEEzpMBxMSIXIawAQAmVn5MR8pwrxnBMZu_bsitsGV3vbTPdJIld66MPU9-msPI29r78S7jEpKdmGxKwsdG7NoZLclbbJrirg07I1_PT5-yVzj9e3maPc1oyISItS62LTHHlIBe20lqnu8xFUqWlc7yoClG5QgvGLSrFIasKp1kNltmaWzYhd_u-m777GVyIZu1D6ZrGtq4bgpEohBQCEnj7D1x1Q9-m2UyWjhJ5xo_dvm3jzDL9LC5D1wzRd20wj8glItcSE4h7sOy7EHpXm03v17bfGgSz88HsfTDJB7Pzwexqbg4TDMXaVceKw-LZL9Qdgnw</recordid><startdate>200401</startdate><enddate>200401</enddate><creator>Ferrara, Elizabeth</creator><creator>Lemire, Jacques</creator><creator>Grimm, Paul C</creator><creator>Reznik, Vivian M</creator><creator>Mendoza, Stanley A</creator><creator>Leake, John A</creator><creator>Benador, Nadine M</creator><general>Springer</general><general>Springer Nature B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QP</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9-</scope><scope>K9.</scope><scope>KB0</scope><scope>M0R</scope><scope>M0S</scope><scope>M1P</scope><scope>NAPCQ</scope><scope>PHGZM</scope><scope>PHGZT</scope><scope>PJZUB</scope><scope>PKEHL</scope><scope>PPXIY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope></search><sort><creationdate>200401</creationdate><title>Mycobacterial peritonitis in pediatric peritoneal dialysis patients</title><author>Ferrara, Elizabeth ; 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According to the most recent data available from the North American Pediatric Renal Transplant Cooperative Study (NAPRTCS), approximately 25% of pediatric PD patients who die succumb to infection. There are no reported cases of Mycobacterium tuberculosis (MTB) or Mycobacterium avium-intracellulare peritonitis in the NAPRTCS registry. With an increasing incidence of MTB worldwide and the impairment of cellular immunity in chronic renal failure patients, it is not surprising that mycobacterium peritonitis can occur in PD patients. We report two pediatric PD patients with mycobacterial peritoneal infection diagnosed over an 11-year period at our institution. One patient presented with a malfunctioning Tenckhoff catheter and again 3 years later with hyponatremia and ascites. The other presented with recurrent culture-negative peritonitis. These cases illustrate the importance of more extensive evaluation of PD complications, to include evaluation for mycobacterium with special media or peritoneal biopsy, in the above clinical settings if the routine work-up is unrevealing.</abstract><cop>Germany</cop><pub>Springer</pub><pmid>14648331</pmid><doi>10.1007/s00467-003-1348-1</doi><tpages>4</tpages></addata></record> |
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subjects | Adolescent Case studies Causes of Child Continuous ambulatory peritoneal dialysis Female Humans Mycobacterium avium complex Mycobacterium avium Complex - isolation & purification Mycobacterium Infections - diagnosis Mycobacterium Infections - microbiology Mycobacterium tuberculosis Mycobacterium tuberculosis - isolation & purification Peritoneal dialysis Peritoneal Dialysis - adverse effects Peritonitis Peritonitis - microbiology Risk factors |
title | Mycobacterial peritonitis in pediatric peritoneal dialysis patients |
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