Improved biocompatibility of small intestinal submucosa (SIS) following conditioning by human endothelial cells

Small intestinal submucosa (SIS) is a naturally occurring tissue matrix composed of extracellular matrix proteins and various growth factors. SIS is derived from the porcine jejunum and functions as a remodeling scaffold for tissue repair. While SIS has proven to be a useful biomaterial for implants...

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Veröffentlicht in:	Biomaterials 2004-02, Vol.25 (3), p.515-525
Hauptverfasser:	Woods, A.M., Rodenberg, E.J., Hiles, M.C., Pavalko, F.M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Basement Membrane - metabolism Biocompatible Materials - chemistry Biocompatible Materials - pharmacology Blood Platelets - metabolism Blotting, Western Cell Adhesion Cell culture Cell Culture Techniques - methods Cells, Cultured Collagen - metabolism Culture Media - pharmacology Endothelial cell Endothelial Cells - metabolism Endothelium, Vascular - cytology Epoprostenol - metabolism Extracellular Matrix - metabolism Fibronectins - metabolism Humans Inflammation Intestinal Mucosa - pathology Intestine, Small - pathology Jejunum - pathology Microscopy, Confocal Microscopy, Electron, Scanning Phosphotyrosine - metabolism Platelet adhesion Prostaglandins I - metabolism Space life sciences Swine Time Factors Transplantation
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