EGF mediates protection against Fas-induced apoptosis by depleting and oxidizing intracellular GSH stocks

Several pieces of evidence have demonstrated the importance of reduction/oxidation (redox) signaling in biological processes, including sensitivity toward apoptosis. In parallel, it was recently reported that growth factors induce the generation of reactive oxygen species (ROS). Therefore, we tested...

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Veröffentlicht in:Journal of cellular physiology 2004-01, Vol.198 (1), p.62-72
Hauptverfasser: Musallam, Lina, Éthier, Chantal, Haddad, Pierre Selim, Bilodeau, Marc
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Sprache:eng
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