The androgen receptor gene CAG polymorphism is associated with the severity of coronary artery disease in men

Summary objective The role of androgens in the pathogenesis of coronary artery disease (CAD) remains controversial. The length of the polyglutamine stretch of the transactivation domain (CAG repeat) of the androgen receptor (AR) inversely affects androgen activity. The aim of this study was to inve...

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Veröffentlicht in:	Clinical endocrinology (Oxford) 2003-12, Vol.59 (6), p.749-755
Hauptverfasser:	Alevizaki, M., Cimponeriu, A. T., Garofallaki, M., Sarika, H.-L., Alevizaki, C. C., Papamichael, C., Philippou, G., Anastasiou, E. A., Lekakis, J. P., Mavrikakis, M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Aged, 80 and over Biological and medical sciences Body Mass Index Chi-Square Distribution Coronary Angiography Coronary Disease - blood Coronary Disease - diagnostic imaging Coronary Disease - genetics Endocrinopathies Estradiol - blood Fundamental and applied biological sciences. Psychology Humans Male Medical sciences Middle Aged Polymorphism, Genetic Receptors, Androgen - genetics Statistics, Nonparametric Testosterone - blood Trinucleotide Repeats Vertebrates: endocrinology
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