New triterpenoidal alkaloids from Buxus sempervirens

Phytochemical studies on the ethanolic extract of the roots of Buxus sempervirens of Turkish origin have resulted in the isolation of two new triterpenoidal alkaloids, (+)-16a, 31-diacetylbuxadine (1), (-)-Nb-demethylcyclomikuranine (2) along with three known natural products, (-)-cyclomikuranine (3...

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Veröffentlicht in:Zeitschrift für Naturforschung C. A journal of biosciences 2002-01, Vol.57 (1-2), p.21-28
Hauptverfasser: Ata, Athar, Naz, Samina, Choudhary, M Iqbal, Atta-ur-Rahman, Sener, Bilge, Turkoz, Songul
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container_title Zeitschrift für Naturforschung C. A journal of biosciences
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creator Ata, Athar
Naz, Samina
Choudhary, M Iqbal
Atta-ur-Rahman
Sener, Bilge
Turkoz, Songul
description Phytochemical studies on the ethanolic extract of the roots of Buxus sempervirens of Turkish origin have resulted in the isolation of two new triterpenoidal alkaloids, (+)-16a, 31-diacetylbuxadine (1), (-)-Nb-demethylcyclomikuranine (2) along with three known natural products, (-)-cyclomikuranine (3), (-)-cyclobuxophylline-K (4) and (+)-buxaquamarine (5) isolated for the first time from this species of genus Buxus. The structures of these new natural products were established on the basis of extensive spectroscopic studies. Compound 1 exhibited antibacterial activity against human pathogenic bacteria and weak phytotoxic activity against Lemna minor Linn.
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subjects Alkaloids - chemistry
Alkaloids - isolation & purification
Alkaloids - pharmacology
Anti-Bacterial Agents - pharmacology
Bacteria - drug effects
Magnetic Resonance Spectroscopy
Magnoliopsida - chemistry
Models, Molecular
Molecular Conformation
Plant Roots - chemistry
Triterpenes - chemistry
Triterpenes - isolation & purification
Triterpenes - pharmacology
Turkey
title New triterpenoidal alkaloids from Buxus sempervirens
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