New triterpenoidal alkaloids from Buxus sempervirens
Phytochemical studies on the ethanolic extract of the roots of Buxus sempervirens of Turkish origin have resulted in the isolation of two new triterpenoidal alkaloids, (+)-16a, 31-diacetylbuxadine (1), (-)-Nb-demethylcyclomikuranine (2) along with three known natural products, (-)-cyclomikuranine (3...
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Veröffentlicht in: | Zeitschrift für Naturforschung C. A journal of biosciences 2002-01, Vol.57 (1-2), p.21-28 |
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creator | Ata, Athar Naz, Samina Choudhary, M Iqbal Atta-ur-Rahman Sener, Bilge Turkoz, Songul |
description | Phytochemical studies on the ethanolic extract of the roots of Buxus sempervirens of Turkish origin have resulted in the isolation of two new triterpenoidal alkaloids, (+)-16a, 31-diacetylbuxadine (1), (-)-Nb-demethylcyclomikuranine (2) along with three known natural products, (-)-cyclomikuranine (3), (-)-cyclobuxophylline-K (4) and (+)-buxaquamarine (5) isolated for the first time from this species of genus Buxus. The structures of these new natural products were established on the basis of extensive spectroscopic studies. Compound 1 exhibited antibacterial activity against human pathogenic bacteria and weak phytotoxic activity against Lemna minor Linn. |
doi_str_mv | 10.1515/znc-2002-1-204 |
format | Article |
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subjects | Alkaloids - chemistry Alkaloids - isolation & purification Alkaloids - pharmacology Anti-Bacterial Agents - pharmacology Bacteria - drug effects Magnetic Resonance Spectroscopy Magnoliopsida - chemistry Models, Molecular Molecular Conformation Plant Roots - chemistry Triterpenes - chemistry Triterpenes - isolation & purification Triterpenes - pharmacology Turkey |
title | New triterpenoidal alkaloids from Buxus sempervirens |
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