Pulmonary complications after esophagectomy
Background. Pulmonary complications are common in patients who have undergone esophagectomy. There are no good predictive variables for these complications. In addition, the role that preoperative treatment with chemotherapy and radiation may play in postoperative complications remains unclear. Meth...
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| Veröffentlicht in: | The Annals of thoracic surgery 2002-03, Vol.73 (3), p.922-926 |
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| container_title | The Annals of thoracic surgery |
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| creator | Avendano, Christopher E Flume, Patrick A Silvestri, Gerard A King, Lydia B Reed, Carolyn E |
| description | Background. Pulmonary complications are common in patients who have undergone esophagectomy. There are no good predictive variables for these complications. In addition, the role that preoperative treatment with chemotherapy and radiation may play in postoperative complications remains unclear.
Methods. We performed a retrospective review of all patients who underwent esophagectomy by a single surgeon at our institution over a 6-year period. Data were analyzed for a correlation between patient risk factors and pulmonary complications, including mortality, prolonged mechanical ventilation, and hospital length of stay.
Results. Complete data were available on 61 patients. Nearly all patients had some pulmonary abnormality (eg, pleural effusion), although most of these were clinically insignificant. Pneumonia was the most common clinically important complication, and 19.7% of patients required prolonged ventilatory support. Significant risk factors identified included impaired pulmonary function, especially for patients with forced expiratory volume in 1 second (FEV
1) less than 65% of predicted, preoperative chemoradiotherapy, and age.
Conclusions. Impaired lung function is a significant risk factor for pulmonary complications after esophagectomy. Patients with FEV
1 less than 65% of predicted appear to be at greatest risk. There also seems to be an associated risk of preoperative chemoradiotherapy for pulmonary complications after esophagectomy. |
| doi_str_mv | 10.1016/S0003-4975(01)03584-6 |
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Methods. We performed a retrospective review of all patients who underwent esophagectomy by a single surgeon at our institution over a 6-year period. Data were analyzed for a correlation between patient risk factors and pulmonary complications, including mortality, prolonged mechanical ventilation, and hospital length of stay.
Results. Complete data were available on 61 patients. Nearly all patients had some pulmonary abnormality (eg, pleural effusion), although most of these were clinically insignificant. Pneumonia was the most common clinically important complication, and 19.7% of patients required prolonged ventilatory support. Significant risk factors identified included impaired pulmonary function, especially for patients with forced expiratory volume in 1 second (FEV
1) less than 65% of predicted, preoperative chemoradiotherapy, and age.
Conclusions. Impaired lung function is a significant risk factor for pulmonary complications after esophagectomy. Patients with FEV
1 less than 65% of predicted appear to be at greatest risk. There also seems to be an associated risk of preoperative chemoradiotherapy for pulmonary complications after esophagectomy.</description><identifier>ISSN: 0003-4975</identifier><identifier>EISSN: 1552-6259</identifier><identifier>DOI: 10.1016/S0003-4975(01)03584-6</identifier><identifier>PMID: 11899202</identifier><identifier>CODEN: ATHSAK</identifier><language>eng</language><publisher>New York, NY: Elsevier Inc</publisher><subject>Adenocarcinoma - surgery ; Adult ; Aged ; Biological and medical sciences ; Carcinoma, Squamous Cell - surgery ; Esophageal Neoplasms - surgery ; Esophagectomy - adverse effects ; Esophagus ; Female ; Forced Expiratory Volume ; Gastroenterology. Liver. Pancreas. Abdomen ; Humans ; Length of Stay ; Male ; Medical sciences ; Middle Aged ; Pleural Effusion - etiology ; Pulmonary Atelectasis - etiology ; Respiratory Tract Diseases - etiology ; Retrospective Studies ; Risk Factors ; Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases ; Surgery of the digestive system ; Tumors</subject><ispartof>The Annals of thoracic surgery, 2002-03, Vol.73 (3), p.922-926</ispartof><rights>2002 The Society of Thoracic Surgeons</rights><rights>2002 INIST-CNRS</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c539t-341b277ef16adccf4754e3c01c3d4255d704f16bb8cbb8d062a5de65c917cc053</citedby><cites>FETCH-LOGICAL-c539t-341b277ef16adccf4754e3c01c3d4255d704f16bb8cbb8d062a5de65c917cc053</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S0003497501035846$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3537,27901,27902,65306</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=13538081$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/11899202$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Avendano, Christopher E</creatorcontrib><creatorcontrib>Flume, Patrick A</creatorcontrib><creatorcontrib>Silvestri, Gerard A</creatorcontrib><creatorcontrib>King, Lydia B</creatorcontrib><creatorcontrib>Reed, Carolyn E</creatorcontrib><title>Pulmonary complications after esophagectomy</title><title>The Annals of thoracic surgery</title><addtitle>Ann Thorac Surg</addtitle><description>Background. Pulmonary complications are common in patients who have undergone esophagectomy. There are no good predictive variables for these complications. In addition, the role that preoperative treatment with chemotherapy and radiation may play in postoperative complications remains unclear.
Methods. We performed a retrospective review of all patients who underwent esophagectomy by a single surgeon at our institution over a 6-year period. Data were analyzed for a correlation between patient risk factors and pulmonary complications, including mortality, prolonged mechanical ventilation, and hospital length of stay.
Results. Complete data were available on 61 patients. Nearly all patients had some pulmonary abnormality (eg, pleural effusion), although most of these were clinically insignificant. Pneumonia was the most common clinically important complication, and 19.7% of patients required prolonged ventilatory support. Significant risk factors identified included impaired pulmonary function, especially for patients with forced expiratory volume in 1 second (FEV
1) less than 65% of predicted, preoperative chemoradiotherapy, and age.
Conclusions. Impaired lung function is a significant risk factor for pulmonary complications after esophagectomy. Patients with FEV
1 less than 65% of predicted appear to be at greatest risk. There also seems to be an associated risk of preoperative chemoradiotherapy for pulmonary complications after esophagectomy.</description><subject>Adenocarcinoma - surgery</subject><subject>Adult</subject><subject>Aged</subject><subject>Biological and medical sciences</subject><subject>Carcinoma, Squamous Cell - surgery</subject><subject>Esophageal Neoplasms - surgery</subject><subject>Esophagectomy - adverse effects</subject><subject>Esophagus</subject><subject>Female</subject><subject>Forced Expiratory Volume</subject><subject>Gastroenterology. Liver. Pancreas. Abdomen</subject><subject>Humans</subject><subject>Length of Stay</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Pleural Effusion - etiology</subject><subject>Pulmonary Atelectasis - etiology</subject><subject>Respiratory Tract Diseases - etiology</subject><subject>Retrospective Studies</subject><subject>Risk Factors</subject><subject>Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases</subject><subject>Surgery of the digestive system</subject><subject>Tumors</subject><issn>0003-4975</issn><issn>1552-6259</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2002</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkN1LwzAQwIMobk7_BGUviiLVfDRp-yQy_IKBgvoc0kuqkbaZSSvsvzfbinv04QjH_S5390PomOArgom4fsUYsyQtMn6OyQVmPE8TsYPGhHOaCMqLXTT-Q0boIISvmNJY3kcjQvKioJiO0eVLXzeuVX45Bdcsaguqs64NU1V1xk9NcItP9WGgc83yEO1Vqg7maHgn6P3-7m32mMyfH55mt_MEOCu6hKWkpFlmKiKUBqjSjKeGASbAdEo51xlOY60sc4ihsaCKayM4FCQDwJxN0Nnm34V3370JnWxsAFPXqjWuDzIjPM1FLiLINyB4F4I3lVx428RbJMFyZUmuLcmVAomJXFuSq76TYUBfNkZvuwYtETgdABVA1ZVXLdiw5RhnOc5J5G42nIk6fqzxMoA1LRhtfXQmtbP_rPIL7K-DZQ</recordid><startdate>20020301</startdate><enddate>20020301</enddate><creator>Avendano, Christopher E</creator><creator>Flume, Patrick A</creator><creator>Silvestri, Gerard A</creator><creator>King, Lydia B</creator><creator>Reed, Carolyn E</creator><general>Elsevier Inc</general><general>Elsevier Science</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20020301</creationdate><title>Pulmonary complications after esophagectomy</title><author>Avendano, Christopher E ; Flume, Patrick A ; Silvestri, Gerard A ; King, Lydia B ; Reed, Carolyn E</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c539t-341b277ef16adccf4754e3c01c3d4255d704f16bb8cbb8d062a5de65c917cc053</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2002</creationdate><topic>Adenocarcinoma - surgery</topic><topic>Adult</topic><topic>Aged</topic><topic>Biological and medical sciences</topic><topic>Carcinoma, Squamous Cell - surgery</topic><topic>Esophageal Neoplasms - surgery</topic><topic>Esophagectomy - adverse effects</topic><topic>Esophagus</topic><topic>Female</topic><topic>Forced Expiratory Volume</topic><topic>Gastroenterology. Liver. Pancreas. Abdomen</topic><topic>Humans</topic><topic>Length of Stay</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Pleural Effusion - etiology</topic><topic>Pulmonary Atelectasis - etiology</topic><topic>Respiratory Tract Diseases - etiology</topic><topic>Retrospective Studies</topic><topic>Risk Factors</topic><topic>Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases</topic><topic>Surgery of the digestive system</topic><topic>Tumors</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Avendano, Christopher E</creatorcontrib><creatorcontrib>Flume, Patrick A</creatorcontrib><creatorcontrib>Silvestri, Gerard A</creatorcontrib><creatorcontrib>King, Lydia B</creatorcontrib><creatorcontrib>Reed, Carolyn E</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>The Annals of thoracic surgery</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Avendano, Christopher E</au><au>Flume, Patrick A</au><au>Silvestri, Gerard A</au><au>King, Lydia B</au><au>Reed, Carolyn E</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Pulmonary complications after esophagectomy</atitle><jtitle>The Annals of thoracic surgery</jtitle><addtitle>Ann Thorac Surg</addtitle><date>2002-03-01</date><risdate>2002</risdate><volume>73</volume><issue>3</issue><spage>922</spage><epage>926</epage><pages>922-926</pages><issn>0003-4975</issn><eissn>1552-6259</eissn><coden>ATHSAK</coden><abstract>Background. Pulmonary complications are common in patients who have undergone esophagectomy. There are no good predictive variables for these complications. In addition, the role that preoperative treatment with chemotherapy and radiation may play in postoperative complications remains unclear.
Methods. We performed a retrospective review of all patients who underwent esophagectomy by a single surgeon at our institution over a 6-year period. Data were analyzed for a correlation between patient risk factors and pulmonary complications, including mortality, prolonged mechanical ventilation, and hospital length of stay.
Results. Complete data were available on 61 patients. Nearly all patients had some pulmonary abnormality (eg, pleural effusion), although most of these were clinically insignificant. Pneumonia was the most common clinically important complication, and 19.7% of patients required prolonged ventilatory support. Significant risk factors identified included impaired pulmonary function, especially for patients with forced expiratory volume in 1 second (FEV
1) less than 65% of predicted, preoperative chemoradiotherapy, and age.
Conclusions. Impaired lung function is a significant risk factor for pulmonary complications after esophagectomy. Patients with FEV
1 less than 65% of predicted appear to be at greatest risk. There also seems to be an associated risk of preoperative chemoradiotherapy for pulmonary complications after esophagectomy.</abstract><cop>New York, NY</cop><pub>Elsevier Inc</pub><pmid>11899202</pmid><doi>10.1016/S0003-4975(01)03584-6</doi><tpages>5</tpages><oa>free_for_read</oa></addata></record> |
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| subjects | Adenocarcinoma - surgery Adult Aged Biological and medical sciences Carcinoma, Squamous Cell - surgery Esophageal Neoplasms - surgery Esophagectomy - adverse effects Esophagus Female Forced Expiratory Volume Gastroenterology. Liver. Pancreas. Abdomen Humans Length of Stay Male Medical sciences Middle Aged Pleural Effusion - etiology Pulmonary Atelectasis - etiology Respiratory Tract Diseases - etiology Retrospective Studies Risk Factors Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases Surgery of the digestive system Tumors |
| title | Pulmonary complications after esophagectomy |
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