Transport across 1,9-decadiene precisely mimics the chemical selectivity of the barrier domain in egg lecithin bilayers

The barrier domain solubility-diffusion theory of lipid bilayer permeability relates the permeability coefficient (Pm) to the solute's partition coefficient (PCbarrier/w) and diffusion coefficient (Dbarrier) in the ordered chain region of the bilayer that serves as the barrier region for polar...

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Veröffentlicht in:	Journal of pharmaceutical sciences 2002-03, Vol.91 (3), p.640-646
Hauptverfasser:	Mayer, Peter T., Anderson, Bradley D.
Format:	Artikel
Sprache:	eng
Schlagworte:	Algorithms Biological and medical sciences Cell physiology Diffusion Eggs - analysis Fundamental and applied biological sciences. Psychology Hippurates - chemistry Hydrogen Bonding Kinetics lipid bilayers Lipid Bilayers - chemistry Lipids Membrane and intracellular transports membrane transport Models, Chemical Molecular and cellular biology partition coefficients peptide permeability Permeability Phosphatidylcholines - chemistry solubility-diffusion theory Solvents
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