Corn Fiber Oil Lowers Plasma Cholesterol by Altering Hepatic Cholesterol Metabolism and Up-Regulating LDL Receptors in Guinea Pigs

To evaluate some of the mechanisms involved in the hypocholesterolemic effects of corn fiber oil (CFO), male Hartley guinea pigs were fed diets containing increasing doses of CFO [0 (control), 5, 10 or 15 g/100 g]. Total fat was adjusted to 15 g/100 g in all diets with regular corn oil. Diets contai...

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Veröffentlicht in:	The Journal of nutrition 2002-03, Vol.132 (3), p.335-340
Hauptverfasser:	Ramjiganesh, Tripurasundari, Roy, Suheeta, Freake, Hedley C., Fernandez, Maria Luz, McIntyre, Jonathan C.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Base Sequence Biological and medical sciences Cholesterol Cholesterol - blood Cholesterol - metabolism Cholesterol 7-alpha-Hydroxylase - genetics Cholesterol 7-alpha-Hydroxylase - metabolism cholesterol 7alpha-monooxygenase cholesterol 7α-hydroxylase Cholesterol, Dietary - administration & dosage Cholesterol, LDL - blood Corn corn fiber oil corn oil Corn Oil - pharmacology Dietary Fats, Unsaturated - pharmacology DNA, Complementary - chemistry Experiments Guinea Pigs Humans LDL receptor Liver - drug effects Liver - metabolism low density lipoprotein cholesterol messenger RNA microsomal cholesterol Microsomes, Liver - drug effects Microsomes, Liver - metabolism Molecular Sequence Data Nutrition Rats receptors Receptors, LDL - drug effects Receptors, LDL - genetics Receptors, LDL - metabolism RNA, Messenger - analysis Sequence Homology
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