α-Synuclein Protects against Oxidative Stress via Inactivation of the c-Jun N-terminal Kinase Stress-signaling Pathway in Neuronal Cells

The expression of α-synuclein, a synaptic molecule implicated in the pathogenesis of neurodegenerative disorders such as Parkinson's disease and Lewy body disease is increased upon injury to the nervous system, indicating that it might play a role in regeneration and plasticity; however, the me...

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Veröffentlicht in:The Journal of biological chemistry 2002-03, Vol.277 (13), p.11465-11472
Hauptverfasser: Hashimoto, Makoto, Hsu, Leigh J., Rockenstein, Edward, Takenouchi, Takato, Mallory, Margaret, Masliah, Eliezer
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Sprache:eng
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