A peritoneal dialysis patient with fatal culture-negative peritonitis
Culture‐negative peritoneal inflammation accounts for between 5 and 20% of cases of peritonitis in peritoneal dialysis patients. Diagnostic yields may be enhanced considerably by reculturing dialysate effluents using appropriate collection methods and optimal laboratory techniques (including prolong...
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| Veröffentlicht in: | Nephrology (Carlton, Vic.) Vic.), 2003-02, Vol.8 (1), p.49-55 |
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| container_title | Nephrology (Carlton, Vic.) |
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| creator | JOHNSON, DAVIDW GRAY, NICK SNELLING, PAUL |
| description | Culture‐negative peritoneal inflammation accounts for between 5 and 20% of cases of peritonitis in peritoneal dialysis patients. Diagnostic yields may be enhanced considerably by reculturing dialysate effluents using appropriate collection methods and optimal laboratory techniques (including prolonged low‐temperature and anaerobic incubations). In patients with persistent culture‐negative peritonitis, consideration should be given to the possibilities of unusual or fastidious microorganisms (especially fungi and mycobacteria) and non‐infective causes (especially drug reactions, malignancy, visceral inflammation and retroperitoneal inflammation). In this paper, an illustrative case of persistent culture‐negative peritonitis is presented followed by a discussion of the investigative approach to such patients, with particular emphasis on differential diagnosis and the limitations of currently available tests. |
| doi_str_mv | 10.1046/j.1440-1797.2003.00119.x |
| format | Article |
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Diagnostic yields may be enhanced considerably by reculturing dialysate effluents using appropriate collection methods and optimal laboratory techniques (including prolonged low‐temperature and anaerobic incubations). In patients with persistent culture‐negative peritonitis, consideration should be given to the possibilities of unusual or fastidious microorganisms (especially fungi and mycobacteria) and non‐infective causes (especially drug reactions, malignancy, visceral inflammation and retroperitoneal inflammation). 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Diagnostic yields may be enhanced considerably by reculturing dialysate effluents using appropriate collection methods and optimal laboratory techniques (including prolonged low‐temperature and anaerobic incubations). In patients with persistent culture‐negative peritonitis, consideration should be given to the possibilities of unusual or fastidious microorganisms (especially fungi and mycobacteria) and non‐infective causes (especially drug reactions, malignancy, visceral inflammation and retroperitoneal inflammation). In this paper, an illustrative case of persistent culture‐negative peritonitis is presented followed by a discussion of the investigative approach to such patients, with particular emphasis on differential diagnosis and the limitations of currently available tests.</description><subject>atypical mycobacteria</subject><subject>bacterial infections</subject><subject>Diagnosis, Differential</subject><subject>Fatal Outcome</subject><subject>Female</subject><subject>Humans</subject><subject>Middle Aged</subject><subject>Mycobacterium tuberculosis</subject><subject>mycoses</subject><subject>Peritoneal Dialysis</subject><subject>peritoneal tuberculosis</subject><subject>Peritonitis - diagnosis</subject><subject>Peritonitis - etiology</subject><issn>1320-5358</issn><issn>1440-1797</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2003</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkUtPwzAQhC0EoqXwF1BO3BLWsR03EpdSSkGqCuLVo-UkNrikD2KHtv8elz44ctqV5puVdgahAEOEgSaX4whTCiHmKY9iABIBYJxGywPU3AuHficxhIywdgOdWDv2EI8TfIwamAGOOYMm6nWCuaqMm02VLIPCyHJljQ3m0hk1dcHCuI9AS-e1vC5dXalwqt69-K12PuOMPUVHWpZWnW1nC73e9l66d-HgoX_f7QzCnBKahhQncSJ1nJF2wkgBjGgoSMpTLTPClIZc5THJQOZapgkmbZ0WGZaakkwxnXDSQhebu_Nq9lUr68TE2FyVpZyqWW0Fx4wCp-1_wRg4TjlNPHi-Betsogoxr8xEViuxS8gDVxtgYUq1-tNBrJsQY7EOXKwDF-smxG8TYimGvUe_eHu4sRvr1HJvl9Wn8P9wJkbDvujzp-vR282zoOQH11OLXw</recordid><startdate>200302</startdate><enddate>200302</enddate><creator>JOHNSON, DAVIDW</creator><creator>GRAY, NICK</creator><creator>SNELLING, PAUL</creator><general>Blackwell Science Pty</general><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7QL</scope><scope>7T7</scope><scope>8FD</scope><scope>C1K</scope><scope>FR3</scope><scope>M7N</scope><scope>P64</scope><scope>7X8</scope></search><sort><creationdate>200302</creationdate><title>A peritoneal dialysis patient with fatal culture-negative peritonitis</title><author>JOHNSON, DAVIDW ; GRAY, NICK ; SNELLING, PAUL</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4349-41626af2b38653d053f0d3979fab35ef0cec23b0acfa96138f9db1af43be5f673</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2003</creationdate><topic>atypical mycobacteria</topic><topic>bacterial infections</topic><topic>Diagnosis, Differential</topic><topic>Fatal Outcome</topic><topic>Female</topic><topic>Humans</topic><topic>Middle Aged</topic><topic>Mycobacterium tuberculosis</topic><topic>mycoses</topic><topic>Peritoneal Dialysis</topic><topic>peritoneal tuberculosis</topic><topic>Peritonitis - diagnosis</topic><topic>Peritonitis - etiology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>JOHNSON, DAVIDW</creatorcontrib><creatorcontrib>GRAY, NICK</creatorcontrib><creatorcontrib>SNELLING, PAUL</creatorcontrib><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Industrial and Applied Microbiology Abstracts (Microbiology A)</collection><collection>Technology Research Database</collection><collection>Environmental Sciences and Pollution Management</collection><collection>Engineering Research Database</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Nephrology (Carlton, Vic.)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>JOHNSON, DAVIDW</au><au>GRAY, NICK</au><au>SNELLING, PAUL</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A peritoneal dialysis patient with fatal culture-negative peritonitis</atitle><jtitle>Nephrology (Carlton, Vic.)</jtitle><addtitle>Nephrology (Carlton)</addtitle><date>2003-02</date><risdate>2003</risdate><volume>8</volume><issue>1</issue><spage>49</spage><epage>55</epage><pages>49-55</pages><issn>1320-5358</issn><eissn>1440-1797</eissn><abstract>Culture‐negative peritoneal inflammation accounts for between 5 and 20% of cases of peritonitis in peritoneal dialysis patients. 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| source | Wiley Online Library - AutoHoldings Journals; MEDLINE |
| subjects | atypical mycobacteria bacterial infections Diagnosis, Differential Fatal Outcome Female Humans Middle Aged Mycobacterium tuberculosis mycoses Peritoneal Dialysis peritoneal tuberculosis Peritonitis - diagnosis Peritonitis - etiology |
| title | A peritoneal dialysis patient with fatal culture-negative peritonitis |
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