C1-inhibitor for prophylaxis of xenograft rejection after pig to cynomolgus monkey kidney transplantation

Early rejection of discordant porcine xenografts in primate recipients is initiated by the intragraft binding of either preformed (hyperacute xenograft rejection) or induced (acute vascular rejection) antiporcine recipient antibodies with subsequent complement activation via the classical pathway. W...

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Veröffentlicht in:	Transplantation 2002-03, Vol.73 (5), p.688-694
Hauptverfasser:	HECKER, Jens M, LORENZ, Ralf, DICKNEITE, Gerhard, NEIDHARDT, Helge, RÜCKOLDT, Horst, WINKLER, Michael, APPIAH, Richard, VANGEROW, Burkhard, LOSS, Martin, KUNZ, Robert, SCHMIDTKO, Jan, MENGEL, Michael, KLEMPNAUER, Jürgen, PIEPENBROCK, Siegfried
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute Disease Animals Biological and medical sciences Complement C1 Inactivator Proteins - therapeutic use Graft Rejection - prevention & control Immunosuppressive Agents - therapeutic use Kidney - pathology Kidney Transplantation - immunology Macaca fascicularis Medical sciences Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases Surgery of the urinary system Swine Transplantation, Heterologous - immunology
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